Insulite Laboratories
Systems That Restore Health
May 2008

David Hite

David Hite, PhD, of Insulite Laboratories' Medical and Advisory Board, is a clinical health educator in chronic conditions management in Sacramento, CA. where he directs self-care skills and disease management education for individuals with Diabetes, hypertension, hyperlipidemia and other disorders. He developed to provide educational support for Diabetics and wrote/produced the DVD "Take Control: Diabetes Basics." Dr. Hite received his PhD in Health Education from City University in Los Angeles and completed further graduate studies at the School of Public Health, Loma Linda University, CA.

Welcome to our 50th edition of Viewpoints, Insulite Laboratories' monthly e-newsletter. Click on In This Issue headlines to read individual articles.


 Woman with sleep mask.
The female of the species may be deadlier than the male, according to poet and writer Rudyard Kipling.

But if she's human, she needs far more sleep than men and suffers more physical and mental problems if forced to go without it, according to a new study.

Lack of sleep can put women at higher risk of developing Diabetes, heart disease, depression and psychological troubles. Women whose sleep is regularly disturbed – and particularly those who have difficulty falling asleep – are more likely to have higher levels in their blood of a substance linked to Pre- and Type 2 Diabetes. Men's health, however, appears to be far less dependent on how well they sleep.

Researchers from Duke University in Durham, North Carolina, asked 210 healthy men and women without diagnosed sleep disorders to fill out a questionnaire on the quality of their sleep. The volunteers were assessed for levels of depression, anger, hostility and how much social support they had. Blood samples were also analyzed.

Around 40% of the participants were classified as poor sleepers. While there was little difference in sleep quality between the sexes, the women were found to have suffered much more when deprived of "snooze time," says the study published in the journal Brain, Behavior and Immunity.

The research team found that sleeping problems, such as poor sleep quality, difficulty falling asleep more than two nights a week or taking longer than 30 minutes to fall asleep, were also linked in the female participants to higher levels of fibrinogen, a clotting factor tied to stroke.

Women with sleeping problems also tended to exhibit higher levels of various markers associated with inflammation, which has been linked to the onset of Pre- and Type 2 Diabetes. Inflammation can also lead to thickening of the arteries, resulting in an increased risk of heart disease.

Those who slept poorly also reported more symptoms of depression, hostility and anger. But the men with sleeping problems showed no increased risk of the conditions that were affecting the women.

Dr. Edward Suarez, associate professor in Duke's department of psychiatry and behavioral sciences, said: "This is the first empirical evidence that supports what we have observed about the role of gender and its effects upon sleep and health.

"The study suggests that poor sleep – measured by the total amount of sleep, the degree of awakening during the night and, most importantly, how long it takes to get to sleep – may have more serious health consequences for women than for men.

"The results were so dramatic that 33% of the women who were poor sleepers had protein levels associated with a high risk of heart disease. Interestingly, it appears that it's not so much the overall sleep quality that was associated with greater risk, but rather the length of time it takes a person to fall asleep that takes the highest toll.

"Women who reported taking half an hour or more to fall asleep showed the worst risk profile."

Dr. Suarez added that the differences between men and women could be attributed to variations in the activity of the number of naturally occurring substances in the body, such as the amino acid tryptophan, the neurotransmitter serotonin and the "sleep" hormone melatonin.

"All of these substances are known to affect mood, sleep, onset of sleep, inflammation and Insulin Resistance," said Dr.Suarez.

The latter disorder is often an underlying cause of Type 2 Diabetes, as well as excess weight and obesity-linked conditions like cardiovascular disease and Polycystic Ovarian Syndrome (PCOS).
 Young girl with book in library.
Physical fitness has tangible effects on performance in the classroom, says a new report.

Girls, in particular, benefit from regular gym classes, according to the findings.

The report, by The Centers for Disease Control focused on 5,000 youngsters from kindergarten to fifth grade. Researchers found that girls who received 70 to 300 minutes of physical education per week scored consistently higher on standardized tests – a definite plus in an increasingly competitive world which places ever greater emphasis on educational qualifications.

More exercise also translated into increased classroom participation and concentration skills among girls. But there was no similar finding in boys, leading researchers to conclude that young males tended to get more exercise through their inclination to play sports like football, baseball and basketball.

Parents and doctors are concerned that an increasing number of school districts are slashing PE to meet budget demands. Under the provisions of the government's No Child Left Behind scheme, math and reading count for more in assessing a school's performance.

As a result, many parents report that their children have gym class only once or twice a week and they fear that the resulting lack of exercise could be affecting the academic development of girls.

Encouraging girls to play soccer is a good antidote to declining gym classes, say exercise experts.
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 Man sitting on a yoga ball.
Home fitness equipment needn't cost you an arm and leg if you want something a little more sophisticated than a jump rope or hand weights.

There are some very reasonably priced items out there, which can help to vary your exercise routine so it doesn't become monotonous and you remain engaged in healthy activity.

A fitness ball can enhance any workout routine, ranging from ab work to push-ups. They're also good for sitting on to improve core strength and posture while you work at a computer at home or watch TV. Expect to pay around $40.

A small heart-rate monitor keeps you posted on how fast your heart is beating to help you stay within a healthy target range and not overdo things. Cost: around $50.

A chin-up bar is perfect for a variety of upper-body exercises. Some models can be used as a foot anchor for stomach crunches. Cost: around $20.

Resistance tubing is a routine-busting alternative to hand weights. The tubes can offer light, medium and heavy resistance to sculpt both your upper and lower body. Prices vary but resistance tubing is quite inexpensive.

All of the above are readily available at sporting goods stores or online.
Insulite Laboratories Systems
Are you an apple or pear?

A recent diet study in the Journal of the American Medical Association compared obese adults with an apple-shaped body, who carry weight around the midsection, with those who have a pear-shaped body with weight around the hips.

Researchers found that "apples," who tend to secrete high levels of insulin, did best on a low Glycemic Index (GI) diet that restricts heavy carbohydrate food like pasta.

The average weight loss in this group on a low GI diet was 13 lbs over six months, compared to 5 lbs on a low-fat diet.

"Pears" lost 10 lbs on both diets over the same period.

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"Ever since I started the Insulite Pre-Diabetes System my blood glucose levels have dropped 15%.

"It's reassuring to know that there is help for me and other people with Pre-Diabetes."

Honolulu, HI
Have You Been Diagnosed with Pre-Diabetes?

If You Have, We're Here to Help You Restore Your Health

Insulite Laboratories is committed to giving you a better understanding of Pre-Diabetes and a common underlying cause of the condition, namely Insulin Resistance-linked excess weight or obesity.

The Insulite Pre-Diabetes System has been scientifically-formulated to help reverse Insulin Resistance - an imbalance of blood glucose and insulin.

Pre-Diabetes is a reversible condition that is diagnosed when blood sugar and insulin levels are higher than normal but not high enough for the onset of Type 2 Diabetes. If neglected, however, Pre-Diabetes can lead to Type 2 Diabetes.

This latter disorder can only be managed for the rest of a Diabetic's life in the vast majority of cases and may require daily injections of insulin. Type 2 Diabetes, itself, is a severely increased risk factor for blindness, heart and kidney disease and the need for amputation.

The Insulite Pre-Diabetes System includes a scientifically-designed combination of nutrients which are primarily designed to increase insulin sensitivity, which can, in turn, prevent the onset of Type 2 Diabetes.

With this system, cells can absorb blood glucose more efficiently for conversion to energy, thereby reducing levels of circulating glucose. A decrease in elevated blood glucose lowers the secretion of insulin.

And when insulin and glucose are in balance, weight loss is facilitated and the symptoms of a related disease like Pre-Diabetes can be reversed before Type 2 Diabetes takes hold.