Insulite Labs
March 2006
IN THIS ISSUE: Insulite Laboritories

Welcome to the twenty-fourth edition of Viewpoints, our monthly e-newsletter.

We at Insulite Laboratories believe that patience is required if you want to achieve lasting weight loss and the greater sense of well being that everyone experiences as a consequent result of improved health.

Extravagant claims made by products that promise rapid weight loss usually lead to bitter disappointment when those excess pounds either don't disappear or come right back because the body hasn't had time to adapt.

Gradual weight loss is much more effective and permanent. As well as switching to a healthy, balanced diet, there are a number of small changes-of-habit you can add to your regular exercise regime that, over time, will help you whittle away at your weight.

Cardiovascular exercises serve the double purpose of improving the condition of your heart while also helping you to lose weight. So take the stairs instead of the elevator at work, trying walking for 15 minutes during your lunch hour and leave your car in the furthest space in the parking lot. You need to get your heart pumping to change your metabolic rate and increase insulin receptor sites on your cell walls to reverse Insulin Resistance-linked excess weight and obesity.

Build arm and leg muscle while you're at work. Sitting on a chair, place your hands on your desk at the same width as that between your hips and push yourself up. Hold that position for 5 seconds, relax back into your seat and repeat. If you're stuck behind a computer all day, you might want to try repeating this "pocket-sized" exercise 3 or 4 times an hour.

Something else to bear in mind is that two's company and so is three when it comes to weight loss. It can be very challenging to maintain a commitment on your own. So try to find a friend to work out with you and share the experience. Exercising with two or more companions is even better because each member of the group will motivate the others.

“Exercise is the chief source of improvement in our faculties.”

- Hugh Blair

Good health opens up so many new possibilities.



Intelligence Report

The way female babies develop in the womb may affect their risk of developing Polycystic Ovarian Syndrome (PCOS) as adults. It could also influence the severity of their symptoms if they do suffer from the disorder.

PCOS is often caused by Insulin Resistance, an imbalance of blood glucose and insulin, which, if left unchecked, can lead to excess weight and obesity. These latter conditions can create high levels of the male hormone testosterone in women, resulting in fluid-filled sacs or cysts on the ovaries that prevent ovulation. Without ovulation, it is impossible to become pregnant. Other symptoms of PCOS include excess facial and body hair, skin conditions and male-pattern baldness in women.

A major on-going population study in Australia, which has examined maternal factors during pregnancy and their impact on the subsequent development of PCOS, is the first to reconcile previous conflicting research on the developmental origins of the syndrome (1).

Dr Michael Davies and a team at the Research Centre in Reproductive Health at the University of Adelaide have been studying a group of young women born between 1973 and 1975. They went back to maternity hospital records and first traced the mothers so that they could then contact and interview the daughters.

Researchers interviewed 544 women who were born between 1973 and 1974. They took a medical history of the young women and compared it with information about their births, including birth weight, placental weight and weight of their mothers at their last clinical examination before giving birth.

Dr Davies told the 21st annual conference of the European Society of Human Reproduction and Embryology : “Our research suggests that, during pregnancy and birth, there are several different factors working through different pathways that are implicated in the overlapping and varying symptoms of PCOS that emerge in the offspring's later life.

“Existing research has already established links between fetal growth restriction, postnatal growth and metabolic disorders such as Diabetes in adulthood. The idea that events in very early life can have an enduring, complex and important influence on subsequent disease is referred to as developmental programming, and this research theme has been applied to PCOS recently.

"Different studies have produced conflicting evidence that shows that large babies grow to become heavier adults with polycystic ovaries, but that the most severe symptoms of PCOS are associated with growth restriction as a fetus.

“Our research examines the relationship between symptoms of PCOS in adulthood and fetal conditions in women born in a major hospital in Adelaide in the 1970s. Our findings support the proposition that there is an inter-generational growth path leading to menstrual irregularity, while, at the same time, other symptoms may be one of number of consequences of restricted fetal growth.”

Symptoms of PCOS were relatively common in many of the women examined. One in five had more facial and/or body hair than normal, while one in four reported menstrual irregularity of greater than four days. Some 5% of women reported that they had an existing diagnosis of PCOS.

“We examined maternal weight in late pregnancy, birth weight and placental weight in relation to the symptoms of PCOS, or an existing or putative diagnosis of PCOS, " said Dr. Davies.

"Compared with their counterparts, young women without a diagnosis of PCOS but with irregular periods were heavier at birth, with larger placentas, and they tended to have mothers who were heavier in late pregnancy. In contrast, women with an existing diagnosis of PCOS tended to have birth weights that were, on average, 4 lbs lighter than women without PCOS and smaller placentas.

“Therefore, our data suggest that different developmental pathways are implicated in the overlapping symptoms of PCOS. One pathway may be mediated by high maternal weight in late pregnancy, which is linked to irregular periods in the daughter, and possibly obesity and weight-related reproduction problems.

"A second pathway may involve reduced placental and fetal growth, which is linked to the more severe symptoms of PCOS in the daughter, usually resulting in an early clinical diagnosis of the syndrome. A fetus that has been affected by restricted growth is more likely to have problems with insulin metabolism in later life due to an underlying metabolic problem.

"In women, this problem appears to be associated with PCOS, and is most evident where there is a constellation of symptoms of increasing severity. Hence, I suspect there are at least two pathways that can give rise to overlapping symptoms.”

Dr Davies said events that occurred not only to the mother but possibly also to the grandmother could have a bearing on the development of a fetus.

“To understand the growth of a child, we need to also understand the growth of the parents and possibly the grandparents. A good predictor of one's own birth weight is the birth weight of one's mother.”

The study shed light on three aspects of the developmental origins of PCOS, he added. “There are reproductive consequences of metabolic programming events that occur during fetal development; we may need to look further back up the generations and look at more factors than previously considered; and finally, adverse events for one generation may have reproductive implications for the next.”

As well as underlying PCOS, Insulin Resistance can also lead to reversible Pre-Diabetes and the cluster of cardiovascular diseases known as Metabolic Syndrome (Syndrome X). All Insulin Resistance-related disorders are a significantly increased risk factor for heart attacks and stroke.


(1) Study sheds light on the development origins of Polycystic Ovarian Syndrome, ESHRE - European Society of Human Reproduction and Embryology, 2005

Click here to learn about systems that can help reverse PCOS (Polycystic Ovarian Syndrome), Pre-Diabetes and Metabolic Syndrome (Syndrome X).


New Research

Omega 3 Fatty Acids May Improve Mood As Well Heart Health

A new report suggests omega-3 polyunsaturated fatty acids can influence mood, personality and behavior, in addition to its benefits for heart health.

In a study of 106 healthy volunteers, researchers found that participants who had lower blood levels of omega-3 polyunsaturated fatty acids were more likely to report mild or moderate symptoms of depression, a more negative outlook and be more impulsive.

The reverse was also discovered to be true. Those with higher blood levels of omega-3s were found to be in better spirits, according to results of a study presented by University of Pittsburgh School of Medicine researchers at the 64th Annual Scientific Meeting of the American Psychosomatic Society in Denver (1).

"A number of previous studies have linked low levels of omega-3 to clinically significant conditions such as major depressive disorder, bipolar disorder, schizophrenia, substance abuse and attention deficit disorder," said Sarah Conklin, a postdoctoral scholar with the Cardiovascular Behavioral Medicine Program in the department of psychiatry at the University of Pittsburgh School of Medicine.

"However, few studies have shown that these relationships also occur in healthy adults. This study opens the door for future research looking at what effect increasing omega-3 intake, whether by eating omega-3 rich foods like salmon, or taking fish-oil supplements, has on people's mood."

The American Heart Association recommends that all Americans consume fish, which is high in omega-3 fatty acids twice a week. Mercury levels in fish have to be taken into account. But this recommendation is based upon evidence that a diet high in fish is associated with improved heart health and reduced risk for heart-related problems. For people who dislike eating fish, omega 3 fatty acids are available as supplements in capsule form.

While the cardiovascular benefit of increasing omega-3 intake is well recognized, relatively little is known of the potential mental health effects among the general public.

The latest study made comparisons in mood by analyzing levels of omega-3 fatty acids in participants' blood and then comparing that data to the participants' scores on three accepted tests for depression, impulsiveness and personality.

The amount of omega-3 circulating in blood reflects dietary intake of the fatty acid. The study did not require participants to make changes in their normal diet habits.

(1) Omega 3 fatty acids influence mood, impulsivity and personality,
UPMC News Bureau, 2006

Click here to read about a system that uses omega 3 fatty acids
to help reverse Metabolic Syndrome (Syndrome X).

Read Previous Issues of Viewpoints

  Weight Loss: Myth or Fact?
Myth: Morning is the best time to work out.

Fact: There is no "best time" to work out and you should exercise when you feel most comfortable.

This could mean 4:00 in the morning or 10:30 in the evening. One thing to keep in mind, however, is that blood pressure is more elevated in early morning for most people.

If you have normal blood pressure, this should not pose a problem. But, if your resting blood pressure tends to be elevated, discuss early morning exercise with your physician before opting for this kind of regime.

For most people, the best thing to do is to try working out at different times of the day and see what works for you.

Dr Mary Shackelton - Medical Director for Insulite Laboratories
Q. What are the health benefits of being lean and active?

A. According to a study of more than 115,000 female American nurses, weight and activity levels are powerful predictors of longevity (1).

Nurses who were obese and inactive had the highest mortality rate, which was 2.4 times that of women who were thin and active. Those who were obese but physically active were still nearly twice as likely to die as those who were lean and active.

However, just being lean did not completely eliminate the risk associated with being inactive. Thin women who were sedentary had a 55% increased risk of dying, compared with thin women who were physically active. The study, published by the Harvard School of Public Health in December 2004 issue of the New England Journal of Medicine, concluded that the healthiest people are those who are both lean and physically active.

Additionally, research on animals confirms that diets that are lower in calories favor longevity and slowed aging. Studies have shown that leaner animals suffer less illness and age better than their overfed counterparts.

Another study, published in British medical journal The Lancet, found that the more a woman weighs the older her cells appear on a molecular level (2).

The study concluded that obesity can add an equivalent of approximately 9 years to a person’s body. Therefore, the benefits of being lean and active can be predictors of longevity and health.

There are many health benefits to staying lean. These include helping to prevent diseases such as:
  • Type 2 Diabetes
  • Joint problems
  • Hypertension (high blood pressure)
  • High cholesterol
  • Cancer
  • Gallbladder problems
  • Coronary artery disease
The benefits of regular physical activity are also numerous and include the following:
  • Helps build and maintain healthy bones, muscles, and joints
  • Builds endurance and muscular strength
  • Helps manage weight
  • Lowers risk factors for Cardiovascular Disease, colon cancer and reversible Pre-Diabetes leading to Type 2 Diabetes
  • Helps control blood pressure
  • Promotes psychological well-being and self-esteem
  • Reduces feelings of depression and anxiety
Staying lean and active will help you avoid many of the diseases of aging. Make it a goal to exercise and eat right for longevity and good health.

(1) Hu FB, et al. Adiposity as compared with physical activity in predicting mortality among women.
New England Journal of Medicine. 2004 December 23; 351 (26):2694-703. PMID: 15616204

(2) Valdes AM, et al. Obesity, cigarette smoking, and telomere length in women.
Lancet. 2005 Aug 20-26;366(9486):662-4. PMID: 16112303

Further reading:

Bozhkov AI. A low-calories diet as a model of life span expansion and study of mechanisms of aging, Adv Gerontol. 2001;8:89-99.

Bengmark S.Impact of nutrition on ageing and disease. Curr Opin Clin Nutr Metab Care. 2006 Jan;9(1):2-7.

“In three weeks I have lost 3 pounds, my sugar level has dropped about 10 points on average, my face has cleared up dramatically and I feel a lot better overall.

"I have told everyone I know about your product and I have been a walking billboard this week! I have had several compliments on my new found appearance...color in my cheeks, very little acne and my face looks great and, even with just 3 pounds gone, people are asking me if I have lost weight!

"I think that every woman that even thinks she may have PCOS needs to know about your products. Especially the women who have been told that they cannot have children because of infertility from PCOS. Every woman should experience the joy of having a child.

"I believe in your product and I would like to get it out there, so women will have a choice.”

- Nina Madewell
  Dickson, TN

Insulite Laboratories would like to share other experiences like this one to inspire our many clients on the same path. Tell us your story and we will use it in a future issue of this newsletter, as well as on web sites and affiliate sites.

If you are uncomfortable with us publishing your full name, we are quite happy to use your initials or first name to preserve your anonymity. We do ask that you include the name of your hometown and state or, in the case of our numerous clients outside the U.S.A., your country. Please email us at


Our Medical & Advisory Board is comprised of health, nutrition and exercise specialists who contribute to product research and development. They also provide oversight for information included in our web sites, newsletters, weekly health support messages and Insulite System materials.

Selected Members provide support, information and guidance to all individuals who contact Insulite Laboratories about their Insulin-Resistance related disorders and implementation of the various Insulite Systems.

Insulite Laboratories recognizes that our customers enjoy a much higher success rate when they receive support for their lifestyle changes. The Board is also an educational resource for healthcare professionals who advocate Insulite Laboratories Systems for their patients and clients.

Over the coming months we would like to feature several of our Board members in Viewpoints, beginning with:

Sari Cohen

Dr Cohen lends her expertise in drug-nutrient interactions, carbohydrate addiction and the pathophysiology of Insulin Resistance, as well as providing professional guidance to individuals with Insulin-Resistance related disorders.

She helped develop the company's 52-week Protocol for customers on the different Insulite Systems and has co-written with Dr. Mary Shackelton, Medical Director of Insulite Laboratories, the Insulite Guide to Reversing Insulin Resistance and Its Related Disorders.

A clinical practitioner in New Hampshire, Dr. Cohen is a graduate of the Southwest College of Naturopathic Medicine and the author of the prize-winning article "Melatonin, Menstruation and the Moon," published in The Townsend Letter for Doctor and Patients.

"I am committed to reversing the growing trend of Insulin Resistance that we see especially in the developed world," says Dr Cohen.

"Insulin Resistance leads to many serious chronic conditions and is usually readily healed with lifestyle changes and nutritional supplementation. This is truly a modifiable health risk that doctors or healthcare practitioners have an obligation to address."

“In my work for Insulite Laboratories, I have come to have so much respect for the dedication of our customers to healing their health conditions and improving their lifestyles. That is hard work!

"The reason I decided to work for Insulite Laboratories is because of the company's mission to really heal the underlying cause of diseases, rather than simply palliate the symptoms. This fits in with my personal philosophy as a doctor."

Have You Been Diagnosed with Excess Weight or Obesity?

If You Have, We're Glad That You Have Found Us.

We're Here to Support You While You Reverse Your Condition

Insulite Laboratories is committed to giving you a better understanding of excess weight and obesity and its underlying cause, Insulin Resistance.

So we are very pleased to announce the imminent introduction of the Insulite System for Excess Weight and Obesity, which has been scientifically-formulated to reverse Insulin Resistance.

Left unchecked, excess weight and obesity may lead to a variety of disorders, including the cluster of cardiovascular diseases called Metabolic Syndrome (Syndrome X), which can result in a heart attack or stroke.

Weight problems can also play a major role in the onset of Polycystic Ovarian Syndrome (PCOS), a leading cause of female infertility as well as skin conditions, excess facial and body hair and male pattern baldness in women.

Another condition linked to excess weight and obesity is reversible Pre-Diabetes. If neglected, this condition often results in the onset of Type 2 Diabetes, which can only be managed for the rest of a person's life and may require daily injections of insulin. Type 2 Diabetes is a major increased risk factor for blindness, amputation, kidney failure and heart disease.

The Insulite System for Excess Weight and Obesity contains a scientifically-designed combination of nutrients which naturally change the interaction of individual cell membranes with insulin and glucose. The formulation is primarily designed to increase the number of insulin receptors on the surface of each cell.

As a result, cells can accept glucose more efficiently, which reduces circulating blood glucose. A decrease in blood glucose lowers the secretion of insulin - a major cause of excess weight gain and obesity. When insulin and glucose are in balance, weight loss is facilitated.

Check next month's edition of Viewpoints for more details.

Did You Know?


Heart disease is America's biggest killer, though it can afflict men and women in contrasting ways. Excess weight and obesity are often an underlying cause of cardiovascular damage for both sexes. But as many as 3 million American women may suffer from a form of heart disease that is fundamentally different from the type that strikes most men.

Instead of developing obvious blockages in the arteries supplying blood to the heart like many men, some women accumulate plaque more evenly inside the major arteries and in smaller blood vessels. In other cases, their arteries fail to expand properly or go into spasm, often at times of physical or emotional stress. This variety of heart disease is often missed by standard tests.

Younger women seem to be particularly prone to these abnormalities, which strangle vital blood flow to the heart muscle, causing severe and often debilitating pain and fatigue as well as sometimes triggering life-threatening heart attacks.

It may explain why some women suddenly have heart attacks even though their arteries look clear. In some cases, women have heart attacks after their doctor has sent them home without treatment. Instead of classic symptoms like crushing chest pain, sweating and shortness of breath experienced by many men, female victims complain of fatigue, an upset stomach or pain in the jaw or shoulder.

Even when they do get medical attention, these women may not benefit from standard drugs and therapies such as bypass surgery and angioplasty to re-open clogged arteries.

"We're realizing that this may be fairly common among women," said George Sopko of the National Heart, Lung and Blood Institute, which is funding research into this form of female heart disease.

"This is changing our thinking about heart disease in many women," added Dr. Sopko.

Right Clothes
“It's very important to have the right clothing. If you throw on an old T-shirt or sweats, it's not going to be inspiring for your workout.”
  - Cheryl Tiegs
A pride in your appearance can give your exercise performance a real boost.


One Hour


Parents are becoming increasingly aware that it's never too early to encourage their children to control their weight with a healthy, balanced diet and regular exercise. Even a small increase in the amount of exercise a child gets can make a big difference in combating weight problems, especially if the youngster is a girl.

Almost a third of young people in the U.S. between the ages of 6 and 19 are either overweight or in danger of becoming so. The problem is particularly acute among young girls, who generally get less exercise than boys of a similar age.

Now, new analyses of obesity research by The Rand Corporation think tank may lead to major changes in the way schools tackle obesity because it recommends extra education funding for exercise.

Researchers studied 11,000 children and compared changes in BMI (body mass index - the standard measurement of height to weight) of obese and overweight girls in kindergarten and first grade. They found that the prevalence of excess weight and obesity among girls fell 10% in schools that gave first-graders just one hour more of exercise time per week than kindergarten pupils.

Doctors and exercise specialists suggest that parents enquire at the schools that their children attend to make sure the correct emphasis is being given to exercise.

Dr. Rebecca Unger, a pediatrician at Chicago's Memorial Hospital, said the research showed the important role that schools can play in preventing obesity and its health ramifications, which, if left unchecked, can lead to heart disease, Diabetes and other disorders at increasingly younger ages.

"This is incredibly serious if you consider the medical and emotional consequences of obesity," she said. "The further along these problems progress, the more at risk these children are."

AppleFoods containing plenty of fiber have numerous beneficial health effects. These can range from regulating blood sugar, which is important for avoiding the onset of Pre- and Type 2 Diabetes, to lowering heart-damaging cholesterol levels and possibly combating certain forms of cancer.

High-fiber foods have more bulk than low-fiber offerings. If taken in the right form at the right time, fiber can sometimes slow the onset of hunger and help keep weight under control.

Always try to take fiber in a natural form and avoid food that has fiber removed, like sugar. Healthy, fiber-rich foods like fruits and vegetables are particularly good at satisfying hunger pangs.

Here's a recipe suggestion for a breakfast dish that's packed with cholesterol-lowering soluble fiber. Leaving the skin on the apple contributes even more fiber and most of the fat is the healthier, monounsaturated variety from the pecans.

1 apple cored and coarsely chopped

1 cup rolled oats

1/2 tsp ground cinnamon

A pinch of kosher salt

2 cups water

2 tbsp pure maple syrup

1/4 cup toasted pecans

Combine the apple, oats, cinnamon and salt in a large microwave-safe bowl of water and stir. Cover and seal with a tight-fitting lid and heat on high for about 8 minutes until the apple pieces are soft and most of the liquid is absorbed.

Stir in the maple syrup. Divide between 2 bowls and top with pecans. Serve immediately.

Insulite Laboratories is Here for You
Insulite Laboratories is Here for You
You are well on the way to reversing your Insulin Resistance and preventing its related conditions such as PCOS (Polycystic Ovarian Syndrome), Metabolic Syndrome (Syndrome X) and Pre-Diabetes. You are also taking important steps to achieving your desired weight loss goal and the healthy lifestyle you deserve.

Remember that persistence is crucial.

We at Insulite Laboratories are committed to your success and your well being. We're here to help you.

Please contact us with any questions or to order the Insulite System, Insulite PCOS System, Insulite MetaX System or the new  Insulite Pre-Diabetes System at

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DISCLAIMER: The information contained in this newsletter is for the sole purpose of being informative. This information is not and should not be used or relied upon as medical advice. Always seek the advice of your physician, nurse or other qualified health care provider before you undergo any treatment, take any medication, supplements or other nutritional support, or for answers to any questions you may have regarding a medical condition.

Nothing contained in or provided through this newsletter is intended to be or is to be used or relied upon for medical diagnosis or treatment. Your use of our newsletter opportunity is subject to certain terms and conditions including, but not limited to, the fact that you have not been seen, evaluated or diagnosed by a qualified medical/health care provider through the use of our newsletter service.

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