Insulite Labs
June 2004 

Welcome to the third edition of Viewpoints, our monthly e-newsletter. Our guiding objective is to support you in achieving a healthy lifestyle through knowledge. An understanding of how our bodies work is the foundation for changing our behavior, reversing Insulin Resistance and its related conditions, losing weight and, essentially, feeling your best.

In this issue we focus on research that shows, increasingly, that Insulin Resistance is the basis for a number of serious health conditions. It is, simply, an “under” disease - underdiscussed, underrecognized, underdiagnosed and undertreated.

Knowledge is power and Insulite Laboratories is here to help.

“Nothing is a waste of time if you use the experience wisely.”

- Auguste Rodin, sculptor

Even a setback can be put to good use.


Syndrome X Heart Risks Reduced by Exercise and Weight Loss

Working off extra pounds can do wonders for the health of those suffering from Syndrome X, which consists of a collection of metabolic abnormalities that put sufferers at risk of a stroke or coronary heart disease. Recent research shows that a combination of exercise and weight loss greatly reduces the dangers of two factors: insulin overproduction and high blood pressure.

An estimated 40 million Americans have Syndrome X. Doctors often overlook the condition, also known as Metabolic Syndrome. These syndromes are characterized by elevated levels of cholesterol and triglycerides, obesity and Insulin Resistance.

A study by Duke Medical Center found that overweight people with Syndrome X, who made lifestyle modifications by exercising and losing weight, had a 47% reduction in insulin overproduction, also called hyperinsulinemia. Patients who exercised but didn’t lose weight had a 27% reduction. The patients who achieved the greatest weight loss showed the most significant improvements in abnormal insulin responses.

Lana Watkins, the study’s lead author, wrote: “A non-pharmacologic treatment for these patients is needed, since drugs prescribed to lower blood pressure have been shown to actually worsen carbohydrate and lipid metabolism in Syndrome X patients, negating the beneficial effects of those drugs.

“In the last five years there has been an increased appreciation that hyperinsulinemia is an independent risk factor for mortality and it can even be seen as a marker or mechanism underlying this increased risk.”



One-in-Five Health Dollars Spent on
Overweight Epidemic

The relationship between obesity and cancer grows ever more disturbing. A report from the National Cancer Institute states that obesity appears to increase the chance of breast cancer in postmenopausal women. It also highlights the link between obesity and cancer of the colon, prostate, endometrium (the lining of the uterus), cervix, ovary, kidney and gallbladder.

This is particularly bad news in light of the fact that more than half of adult Americans are now overweight to some extent. Obesity is defined as someone having greater than 50% body fat.

Although there are many theories for how obesity increases cancer risk, the exact mechanism is not yet known. But one-in-five health dollars is now spent on trying to counter the obesity epidemic, which has been growing for 30 years and shows no sign of going into reverse. One of the cornerstones of this epidemic is Insulin Resistance, with greater consumption of carbohydrates setting the stage for the onset of the condition.

SOURCE: National Cancer Institute: Cancer Facts, September 2001

DR. MARY'S VIEW:     “Reducing insulin levels may impact the formation of cancer.”

Dr. Mary ShackeltonCancer has never more visible in the news than it is today. Many people are fearful of receiving a cancer diagnosis, yet most do not know how to reduce their risk of getting the disease.

While the conclusions about weight loss and cancer reduction are not clearly drawn, additional research concludes that insulin levels are a factor in the growth of cancer cells in a laboratory setting. It does, therefore, seem logical to conclude that reducing a person’s insulin levels may impact the formation of cancer.

The reduction of insulin production is also critical for weight loss as well as reversing Polycystic Ovarian Syndrome (PCOS), cardiovascular disease and high blood pressure.

Dr. Mary Shackelton, MPH ND, is the Medical Director of Insulite Laboratories.


Myth: High-protein diets are dangerous.

Fact: There is little evidence to support this assertion. In fact, research has shown that the more protein you consume, the better your cardiovascular disease profile is, the leaner, more metabolically active body mass you have, plus better sugar stabilization.

Unless someone suffers from kidney impairment, diets that emphasize protein are healthier than eating habits based on carbohydrate consumption.


Q. Do carb-blockers really work?

A. Carb-blocker diet pills claim that you can lose weight without changing your diet. The pills work by inhibiting the metabolism of carbohydrates into stored fat. But there are no clinical studies performed by mainstream medical and research communities to suggest they work in the long-term. As we know, gradual weight loss is far more likely to be permanent.

The critical ingredient of these products is called phaselous vulgaris, an extract from the northern white kidney bean. This extract interferes with an enzyme in the body called alpha-amylase that breaks down carbohydrates into glucose. Instead of carbohydrates being broken down and turning to fat, the carbs are excreted from the body before they can enter the bloodstream.

Even though the action mechanism for this product is clear, the effectiveness has not yet been determined. There is no evidence that people are actually losing weight.

Click here for FAQs

“I have reduced my waist size considerably after only 5 months on the Insulite System. At age 67, I look and feel great and have recommended Insulite to my daughter. Our entire family has benefited from the carbohydrate reduction guidelines in your Nutritional Plan.”

Madison, Wisconsin

The association between Polycystic Ovarian Syndrome (PCOS) and Insulin Resistance is well-known. Obesity is a major cause of PCOS and Insulin Resistance is an underlying factor in obesity. PCOS is an imbalance of hormones linked with the way the body processes insulin. Women who suffer from the syndrome are at far higher risk of developing breast cancer, Type 2 Diabetes, hypertension and cardiovascular disease.

Reversing Insulin Resistance, and thereby balancing hormones is vital for combating PCOS which also causes menstrual irregularities and infertility.


“You may have to fight a battle more than once to win it.”

Margaret Thatcher.

Try, try and, if necessary, try again until you
accomplish your goals


Losing weight is a gradual process and best undertaken step-by-step. The underlying science behind behavioral change indicates that your brain must habituate or normalize to these changes – a slow and strategic transition is best.

WEANING YOURSELF OFF PASTA is much easier than it sounds! If these tempting but high-carb noodles form the centerpiece of your meal, you can opt for the whole wheat variety now widely available, as well as slowly introduce healthy elements into the mix.

We suggest using olive oil in lieu of creamy sauces, by gently sautéing chopped garlic and green onions or shallots and fresh herbs like oregano and basil. To further enrich and thicken your sauce, add chopped tomatoes. (Skins are easily removed by placing the tomatoes in just-boiled water for three minutes.)

You can slowly reduce the pasta portion of the meal by incorporating some of your favorite vegetables such as chopped, cooked spinach, broccoli, cauliflower, zucchini or others into the pasta. Remember, steaming vegetables is best! For some crunch, try adding a handful of sliced nuts that have been roasted at 400 degrees for 7-10 minutes on a baking sheet with non-stick spray. Or add some small pieces of turkey breast, fish, steak or hamburger that have been broiled or grilled.

If your pasta seems “lonely” without cheese, try sprinkling part-skim, low-fat mozzarella or feta, or mixing in 1-2 Tbsp. of low-fat cottage cheese.

Be creative in making the pasta colorful and healthful as you aim to make it just 30-40 per cent of your plate.

Walking the talk: As you increase your exercise regime, put a spring in your step by reminding yourself of the many benefits you are achieving:

  1. Using excess calories
  2. Increasing your metabolic rate (e.g. the rate at which you burn calories)
  3. Controlling appetite and cravings
  4. Improving self-esteem, which is linked with greater weight loss success
  5. Increasing lean body mass
  6. Improving mood, which may reinforce more exercise
  7. Reducing stress, which can lead to binge eating
  8. Improving sleep (fatigue can lead to poor diet planning and binge eating)

You are well on your way to achieving your desired weight loss goal and the healthy lifestyle you deserve.

Remember that persistence is the key.
We at Insulite Laboratories are committed to your success and your well being.

We're here to help you. Please contact us with any questions or to order the Insulite System at

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