Insulite Laboratories
Systems That Restore Health
June 2008

Dr. Sheri Colberg

Dr. Sheri Colberg is Director of Exercise Physiology for Insulite Laboratories where she develops exercise protocols that focus on the prevention and management of insulin-related disorders.

An Associate Professor of Exercise Science at Old Dominion University in Norfolk, Virginia, she is funded by the American Diabetes Association, among other organizations, for her research on exercise and Diabetes.

Dr. Colberg is Executive Director of the Lifelong Exercise Institute which strives to improve the health of anyone suffering from Diabetes or obesity. She is the author of five books, including The Diabetic Athlete, Diabetes-Free Kids and 50 Secrets of the Longest Living People with Diabetes, as well as co-author of an upcoming book, "Biggest Loser:" Matt Hoover's Guide to Life, Love, and Losing Weight.

Welcome to our 51st edition of Viewpoints, Insulite Laboratories' monthly e-newsletter. Click on In This Issue headlines to read individual articles.


 Plus-sized woman with hands over heart.
Researchers say they have developed a more accurate method of predicting if a woman is at risk of heart disease - a disorder closely linked with obesity.

Current methods were developed 40 years ago and often fail to pick up women who are at risk.

But the new method, called The Reynolds Risk Score, considers more than just traditional risk factors such as age, blood pressure, cholesterol level and smoking. It aims to predict a 10-year risk of heart disease.

New factors taken into consideration include parental history of heart attack before the age of 60 as well as levels of C-reactive protein, which has been linked to clogged arteries and damage to blood vessels in the heart.

The researchers, from Brigham and Women's Hospital in Boston, hope their work will lead to more at-risk women being identified and offered drugs as well as lifestyle interventions to reduce their risk.

Reporting in the Journal of American Medicine, they found that the current risk assessment measures failed to spot up to 20% of women who suffered from heart disease but did not display any of the traditional risk factors.

When they applied the new system, they found many women rated under the old measures of having a 10-year risk of heart disease of less than 20% had to be reclassified. In some the risk was increased, but in others it came down.

Roger Blumenthal of Johns Hopkins University School of Medicine in Baltimore said: "Physicians should incorporate these factors into their testing and decision-making about which women are most likely to develop cardiovascular disease.

"And physicians should intervene with lifestyle changes and drug treatment before symptoms start to appear. Our best means of prevention is through early identification of those most at risk."

An underlying cause of heart disease-related obesity is Insulin Resistance - an imbalance of glucose and insulin levels, which can also lead to Polycystic Ovarian Syndrome (PCOS).

This latter condition is a leading cause of menstrual irregularly and heart-breaking female infertility.
 Woman getting mammogram.
Obese women are a massive 50% more likely to die of breast cancer than females of a healthy weight, according to a new report.

Those who are heavily overweight have a higher risk of developing the disease or being diagnosed with breast cancer at a later stage and also getting less effective treatment.

A study of almost 3,000 women indicated that breast cancer in obese women was more advanced when diagnosed, with lower survival rates and a higher chance the disease would recur after treatment.

Nearly 88% of women who were not obese survived more than five years compared with 83% of obese women, according to Belgian research. Some 76% of women who were not obese lived for five years without the disease returning, whereas the figure dropped to 70% among obese women.

Another study from Geneva, Switzerland, found that obese women were 80% more likely to have their cancer diagnosis made at a later stage than non-obese women.

The delay is thought to be down to greater difficulty in finding small lumps. Some women are also embarrassed about their size, which puts them off the idea of being examined.

The Geneva Cancer Registry used data on 460 women diagnosed with invasive breast cancer between 2003 and 2005. It found obese women were 80% more likely to be diagnosed with advanced disease. It is thought that higher oestrogen levels in obese women's bodies may play a role in driving the growth of invasive tumors.

A balanced, nutritious diet combined with regular exercise can provide the groundwork for weight loss to help restore health and greatly reduce the risk of the onset of breast cancer.
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 Woman exercising at gym on treadmill.
In today's world of ever-changing fitness fads, exercise equipment comes and goes. But, just occasionally, someone creates a machine that really works and stands the test of time.

Two of today's most popular fitness machines are the treadmill and the elliptical trainer. But is one more effective than the other at achieving and maintaining fitness?

This month we focus on the treadmill and next month we'll look at the elliptical.

The treadmill enables an exerciser to walk, jog or run without leaving the gym. It can also simulate hill-climbing.

A treadmill is a great way to burn calories, build bone density, maintain good cardiovascular health and increase energy levels. Most power treadmills offer a number of pre-set programs and intensity levels.

You can program in your personal information (i.e. age, weight, height, fitness level etc.). Then, you may choose a pre-set program, such as 'killer hill' or 'weight-loss', and the unit will automatically adjust the workout to fit your specifications.

If you'd rather manually control your treadmill, you can bypass the pre-set programs and adjust the incline, speed and duration yourself. And even if you've chosen a pre-set program, you have the option of changing the incline level or speed level at any time.

Beginners should start at a lower intensity level and work their way up to a higher one, as fitness improves. For the seasoned athlete, increasing the incline and the speed to accommodate certain levels of fitness can provide interesting new challenges.

Running on a treadmill with a cushioned running surface provides less impact on the knees, shins, ankles, back and joints than does running on pavement. As a result, a person using a treadmill is less likely to sustain a running injury than one who runs upon a harder surface. Nonetheless, a runner's body will still experience impact when the foot lands on the belt and bears up to 2 1/2 times body weight.
Insulite Laboratories Systems
Even the courts are on your side when it comes to trying to lose weight.

A federal judge has turned back a challenge from the New York State Restaurant Association by upholding a NYC regulation requiring calories to be posted on the menus of some restaurant chains like McDonald's, Olive Garden and TGI Fridays.

"It seems reasonable to expect that some consumers will use the information to select lower-calorie meals and these choices will lead to a lower incidence of obesity," said U.S. District Judge Richard Howell.

Menus in chain restaurants in big cities throughout America are now expected to follow suit.

Quick Links
"I started the Insulite PCOS System a couple weeks ago and what a major difference it has made in my health.

"I'm not as fatigued as I used to be. For the first time in a long time I have more energy and it's increasing daily. My sweet tooth is almost gone. I have more control over what I put in my mouth. I don't wake up hungry any more. I'm working out 3 days a week and not feeling exhausted after 30 minutes.

"My waistline is finally starting to SHRINK. I've lost a lot of water weight and still losing. Which is so shocking because on any other program I've been on by the 5th day my body starts to retain fluids. Not with this system.

"Only 2 weeks into this program and I've seen more results than I've ever seen with anything else. I don't know what I'll be saying 3, 6, 9 or 12 months from now.

"I'm looking forward to a healthier me in 2008 and I say this with confidence because I have the Insulite PCOS System on my side.

"Thank you once again for what you have done. It means a lot to me and I really appreciate each of you!!"

Denise L
Have You Been Diagnosed with Polycystic Ovarian Syndrome (PCOS)? Or Do You Think You Might Have This Condition?

If You Have, We're Here to Help You Restore Your Health

Insulite Laboratories is committed to giving you a better understanding of PCOS and a common underlying cause of the condition, namely Insulin Resistance-linked excess weight or obesity.

PCOS is a leading cause of menstrual irregularity and female infertility, as well as skin conditions like acne and brown patches, chronic fatigue and mood swings, excess facial and body hair and male pattern baldness in women.

Overweight and obese women are prone to PCOS but females of normal healthy weight and even those who are lean are also vulnerable.

PCOS can strike women of child-bearing age and those who are post-menopausal.

Despite having many or all of the classic symptoms, many women do not even know they have PCOS.

The Insulite PCOS System has been scientifically-formulated to help reverse Insulin Resistance - an imbalance of blood glucose and insulin levels.

This condition reduces insulin sensitivity, which, in turn, can be an underlying cause of the onset of PCOS. as well as the cluster of increased risk for cardiovascular disease called Metabolic Syndrome (Syndrome X) and Pre- and Type 2 Diabetes.

Once Insulin Resistance has been reversed, it's possible to better manage or even reverse the symptoms of PCOS.

To discover more about Polycystic Ovarian Syndrome and learn of women's experiences on the Insulite PCOS System, click on the address below.