Insulite Labs

Welcome to the fourth edition of Viewpoints, our monthly e-newsletter.

We at Insulite Laboratories are gratified by the announcement this month that the U.S. Government has re-defined obesity as a medical condition. This is good news indeed for those of you dealing with obesity.

With more than 60% of Americans overweight and 30% obese, the move has been a long time coming. Medical research has shown that Insulin Resistance is the key factor in being overweight. We are dedicated to helping you reverse this condition and avoid its serious implications for your health.

We hope that obesity’s new status will encourage you to think about improving your health and, consequently, your life.

Let Insulite Laboratories be an importance resource in achieving that goal.

“In the middle of difficulty lies opportunity.”

- Albert Einstein

Rise to the challenge of succeeding.


1-in-5 Pre-Menopausal Women May
Suffer From PCOS

The prevalence of Polycystic Ovarian Syndrome (PCOS) makes for unsettling reading. As many as 1-in-5 pre-menopausal women may suffer from this condition, which is caused by an imbalance of hormones linked to the way the body processes insulin.

Precise figures for the incidence of PCOS, also known as Stein-Levanthal Syndrome or Chronic Anovulatory Syndrome, are hard to pin down because many women could be asymptomatic - i.e. there is no single symptom that guides an individual to get a clinical diagnosis. Each woman will have a different set of symptoms.

But PCOS is the most common endocrine, or hormonal, problem in women who menstruate, affecting approximately 7% of all females of reproductive age in America. Some 40% of women with a family history of PCOS will inherit the condition. Of those diagnosed with PCOS, 90% have hyperinsulinemia, or insulin overproduction, while 40% will be significantly overweight.

Up to 70% of PCOS sufferers have some degree of Insulin Resistance, the condition in which the surface of the cells has insufficient insulin receptors to absorb glucose (blood sugar). Denied entry to the cell to become energy, glucose remains in the blood stream where it causes elevated blood sugar, which is sent to the liver. It is then stored throughout the body after being converted to fat.

Research suggests that early detection and treatment of Insulin Resistance could achieve dramatic improvements in PCOS-related conditions such as cardiovascular disease, Type 2 Diabetes, infertility-elevated cholesterol levels, cancers connected with estrogen-excess and hypertension.

In addition to Insulin Resistance, common PCOS symptoms include obesity and menstrual irregularities like the absence of menses or heavier than normal bleeding. Other symptoms are multiple ovarian cysts, acne and signs of excess of the male hormone androgen– e.g. facial hair growth and male pattern baldness.

Obesity is the major underlying factor that causes PCOS. Insulin Resistance, in turn, is the major cause of obesity. However, lean women can also have PCOS. Excess weight gain increases the conversion of androgens to estrogens. This imbalance of hormones, which causes PCOS, often seems linked with the way the body processes insulin.

The pancreas produces insulin, which regulates the body’s use of glucose. Insulin problems can cause high levels of male hormones in women, increasing the number of circulating estrogens, which directly affect the production of cystic follicles on the ovaries.

The natural treatment of PCOS should begin with lifestyle changes to reverse Insulin Resistance. A plan to lose weight through exercise and eating more healthfully, combined with a regime of nutritional supplements, can reverse this condition.

Click here to learn about the Insulite System’s Pure Natural Ingredients.



Childhood Eating Habits May Be the Spur

A recent study suggests that Insulin Resistance may begin earlier than was previous thought by the medical community. Researchers discovered that very young rats fed a high carbohydrate diet over a 24-day period developed hyperinsulinemia, the overproduction of insulin.

In humans, this condition is caused by Insulin Resistance which can lead to PCOS as well as Syndrome X or Metabolic Syndrome. These latter two syndromes consist of a collection of metabolic abnormalities that put sufferers at risk of a stroke or coronary heart disease.

The researchers concluded that the biological, cellular and molecular changes that brought on hyperinsulinemia in the rats would form the basis for the onset of obesity in adulthood.

SOURCE: Neonatal Nutrition: metabolic programming of the pancreas and obesity, Exp Biol Med 2003 Jan; 228(1):15-23

DR. MARY'S VIEW:     “It’s never too early to change your eating habits or exercise routine.”

Dr. Mary Shackelton This study clearly shows that what animals eat in the first few weeks of life can impact their biochemical reaction to food even into adulthood. Insulin Resistance may have earlier origins that we previously thought regarding the predisposition towards having a pancreas that over-produces insulin.

We know that Insulin Resistance stems in adulthood from the high consumption of carbohydrates, lack of physical exercise and nutrient deficiencies. But we now have information that may clarify why some people could be more predisposed to Insulin Resistance than others.

These findings may be motivational for families. If children frequently eat meals that are consistently high in carbohydrates, they are more likely to struggle in their adult years with obesity.

Another study,* released this month, suggests that children who watch more than two hours of television a night seem to be at a higher risk of becoming obese or smokers as adults. Researchers assessed, at regular intervals, 1,000 people born in Dunedin, New Zealand, in 1972-73 until age 26.

They investigated links between childhood TV viewing and body mass index, cardio-respiratory fitness, cholesterol levels, smoking status and blood pressure. The study discovered that even an average weeknight TV viewing of one to two hours between the ages of 5 and 15 was associated with higher body-mass indices, lower cardio-respiratory fitness, increased smoking and raised cholesterol.

Insulin Resistance is the major underlying cause of obesity. But the good news is that it’s never too early to change your eating habits or exercise routines.

Dr. Mary Shackelton, MPH ND, is the Medical Director of Insulite Laboratories.

*Source: Dunedin Multidisciplinary Health and Development Research Unit, New Zealand, reported in The Lancet, London.


Myth: Rapid weight loss promised by new diets is long-lasting.

Fact: Research shows that the rapid weight loss promoted by most fad diets is almost immediately followed by rapid weight gain. Your body has a memory and, if you’ve been overweight for a while, it recognizes that weight level as normal.

When you lose weight quickly, your body doesn’t have time to get used to the change. It registers the rapid weight loss as abnormal so that, once you stop the diet, the body tries to return as quickly as possible to the normal retaining of fat.

The best way to avoid the “rebound effect” is to acclimate your body to change by losing weight gradually.


Q. Is Insulin Resistance the same thing as Type 2 Diabetes?

A. No. Insulin Resistance may occur for many decades
before Type 2 Diabetes is diagnosed. With Insulin Resistance, the pancreas is producing too much insulin. With Diabetes, the pancreas can no longer produce insulin.

If treated early, Insulin Resistance does not eventually become Diabetes and does not require the daily administration of medication to control the disease.

I would like to emphasize that, with a proper diet combined with nutrients and a moderate exercise plan, you can reverse Insulin Resistance, which will ultimately ensure the prevention of Diabetes.

Click here for to read “Pre-Diabetes – Are You at Risk?” by Dr. Mary Shackelton, MPH ND

“I have been following the guidelines in your newsletter and have lost even more weight.”

Dr. MJ Lewis
Honolulu, HI

Research suggests that group support can be a big help in shedding extra pounds. Scientists across America compared people who were attempting to lose weight on their own with a group enrolled in a commercial weight loss program. A total of 400 adults were divided into either the “self-helpers” or the “commercial program group.”

The “self-helpers” met with a dietician several times who advised about healthy eating and exercise, while those in the commercial program attended weekly meetings where they were weighed in, provided with educational material and given social support. Weight loss was monitored every 3-4 months for 2 years. At the end of the study, 50% of those in the commercial program were able to lose “significant amounts of weight” while only 29% of the “self-helpers” were able to achieve the same degree of weight loss.

Source: Weight loss with self-help compared with a structured commercial program. S. Heshka, J. Anderson, R. Atkinson, et al., JAMA, 2003, vol. 289, pp. 1792--1798  

Women who train in a group exercise class are better able to stick to a regular fitness routine. Group classes offer social and moral support and help to boost motivation.

Click here to see the kind of Support Messages Insulite Customers receive every week.

“Just go out there and do what you have to do.”
  - Martina Navratilova
Attitude is a major force in achieving success.


Most people have heard of aerobic exercise. But do you know how to gauge whether you are actually experiencing aerobic activity?

AEROBIC EXERCISE IS ANY EXTENDED ACTIVITY that increases your respiratory rate by using the large muscle groups at a regular and even pace. Examples include brisk walking, jogging, bicycling, swimming, aerobic dancing and racquet sports. There’s also rowing, ice or roller skating, skiing, hiking or using a stationary bike or treadmill.

To benefit from aerobic activity, try to get your heart rate into "a target heart zone," which is 50-75% of your maximum heart rate. Use the chart below to determine your own “target heart zone.”

Age Target Heart Zone (50-75%) Average Maximum Heart Rate (100%)
20-30 98-146 beats per minute 195 beats per minute
31-40 93-138 185
41-50 88-131 175
51-60 83-123 165
61+ 78-116 155

To determine if you are exercising in your target heart zone, take your pulse at your wrist or neck for 6 seconds then multiply by 10. If your heart rate is higher than the target heart zone, slow down just a bit. If it’s below, increase your speed slightly.

When you are returning to exercise or beginning for the first time, aim for the lower number (50%) in the range for your heart zone and slowly build to the higher number (75%).

Don’t forget to consult a physician before beginning an exercise regime if your doctor has ever told you have heart problems.

Summertime and the living is easy. Now is the time for outdoor grilling and Portobello mushrooms are ideal with their delicious flavor, size and meaty texture. Here’s a recipe that is quick, tasty and nutritious and can also be prepared indoors under the broiler.

Grilled Portobello Mushroom Caps

  • 1 pound Portobello mushroom caps
  • 2 tablespoons olive oil
  • 2 tablespoons chopped garlic
  • 2 tablespoons chopped fresh thyme leaves
  • salt and pepper to taste
Remove any stems and use a damp towel to gently clean the mushroom caps. Blend the olive oil and garlic and brush the mixture on the underside of the mushroom caps. Season the mushrooms with salt, pepper and thyme. Grill until tender, which takes approximately 7 to 9 minutes, depending on size.

Serves 2 to 4 people.

You are well on the achieving your desired weight loss goal and the healthy lifestyle you deserve.

Remember that persistence is crucial.
We at Insulite Laboratories are committed to your success and your well being.

We're here to help you. Please contact us with any questions or to order the Insulite System at

Quick Links...

voice: 888-986-4325 or 1-970-679-8608