Insulite Labs
July 2005
IN THIS ISSUE: Insulite Laboritories

Welcome to the sixteenth edition of Viewpoints, our monthly e-newsletter.

We at Insulite Laboratories know that the prospect of trying to adopt a more nutritious diet and get more exercise can be daunting, even if you're aware of the benefits that come from losing weight. But we're here to help in any way we can with support and information. In fact, part of our philosophy is that the more information you have about the relationship between weight loss and a healthier lifestyle, the easier it is to move along the path to a greater sense of well being.

Getting a good night's sleep, for instance, can give you an edge if you want to avoid becoming overweight. Lack of sleep has a direct effect on how you eat. It boosts levels of a hormone called ghrelin, which stimulates appetite, while at the same time lowering the presence of leptin, a hormone which sends a message to the brain that the body has enough food.

With their jam-packed schedules, Americans often try to cut back on the hours they allocate for sleep. Yet adults need an average of 8 hours a night to function properly. So always try to find time for a full night's sleep.

Insomnia, on the other hand, can be a problem in more ways than one. Sleep-deprived people eat more because they're awake longer, they're hungrier and they have greater access to food. People are also usually sedentary during that extra waking time, with the most popular "activities" being watching TV, reading and surfing the Internet.

Nearly half of American adults report experiencing insomnia at some time or other. Caffeine late in the day should definitely be avoided and don't forget that it lurks in chocolate, tea and sodas as well as in coffee. Other tips for overcoming insomnia include not napping during the day or eating in bed and finishing rigorous exercise three hours before bedtime.

Sleep is one of the most important needs in life, so try and make sure it's a vital ally in your efforts to lose weight and feel great.

“Dogs are not our whole life but they make our lives whole.”

- Roger Caras

Canines are such great company, especially when you want to walk for exercise.
Exercise with a Dog


Intelligence Report


Pregnant woman who are obese could be storing up fertility problems for their daughters, including Insulin Resistance and Polycystic Ovarian Syndrome (PCOS).

Researchers at the University of Adelaide in Australia found that baby girls born to obese mothers were more likely to have irregular periods as adults. The result, they warn, could be increasing levels of infertility as obesity levels soar in the Western world.

The findings were presented to the European Society for Human Reproduction and Embryology conference in Denmark. Lead researcher Dr. Michael Davies, of Adelaide University's Research Center in Reproductive Health, said: “We may reasonably expect an epidemic of menstrual and fertility diseases as a consequence.”

Dr. Davies' team interviewed 544 women who had been born between 1973 and 1974, which meant they were now aged between 30 and 32. The women were asked about their medical history, while their medical records were checked to assess their own birth weight, as well as the weight of their mothers at the last clinical examination before they had given birth.

The women who reported to researchers that they had irregular periods were far more likely to have been large babies and their mothers were more likely to have been obese while carrying them in the womb. These women also reported symptoms linked with Polycystic Ovarian Syndrome (PCOS), a leading cause of female infertility.

PCOS is the most common endocrine (hormonal) disorder among women who menstruate and may affect up to 5-10% of women of reproductive age in America. The disorder is also known as polycystic ovaries, Sclerocystic Ovarian Disease, Stein-Leventhal Syndrome and Polycystic Ovarian Disease.

The symptoms can vary widely from woman to woman. Not all women have all the symptoms, which range from irregular or completely absent periods to hirsuitism (excessive facial or body hair), ovarian cysts and Alopecia (male pattern hair loss). Other symptoms can include obesity, acne and skin tags, Acanthosis Nigricans (brown skin patches), high cholesterol levels, exhaustion or lack of mental alertness and decreased sex drive.

Doctors very often misdiagnose PCOS. This situation became of critical concern after a University of Pittsburgh study1 in 2000 found that PCOS sufferers have a higher risk of coronary heart disease. Researchers discovered an increased association between PCOS and atherosclerosis, which occurs when fatty deposits called plaque cling to the interior walls of the arteries, leading to blockages that can cause heart attacks or stroke.

Not only do PCOS sufferers have higher rates of plaque build-up but those over 45 also have thicker deposits of plaque. In addition, the imbalance of glucose and insulin levels caused in women with PCOS leads to a lowering of “good” cholesterol and an increase in the level of triglycerides, which are fat-storing substances carried through the bloodstream to the tissues. These factors also increase the risk of heart attacks and stroke.

An underlying cause of PCOS can be Insulin Resistance, which leads to an imbalance of glucose and insulin in the blood stream. Left unchecked, it may result in weight gain and obesity, which, in turn, can lead to the imbalance of hormones that cause PCOS. Insulin Resistance can also lead to the cluster of cardiovascular disorders known as Metabolic Syndrome, as well as Pre-and Type II Diabetes.

Adelaide University’s Dr. Davies suggested two mechanisms lay behind the abnormalities shown in his study.

“One pathway may be mediated by high maternal weight in late pregnancy, which is linked to irregular periods in the daughter and possibly obesity and weight-related reproduction problems,” he said.

“A second pathway may involve reduced placental and fetal growth, which is linked to the more severe symptoms of PCOS in the daughter, usually resulting in an early clinical diagnosis of the syndrome.”

Source: 1 Findings published in the November 2000 issue of Arteriosclerosis, Thrombosis and Vascular Biology

(See also Consult Dr. Mary)

Click here to learn about a system that helps reverse Insulin Resistance, an underlying cause of PCOS.


New Research


Even modest changes in lifestyle can make a big difference when it comes to the risk of developing Pre-Diabetes, which may lead to potentially life-threatening Type 2 Diabetes.

Both these disorders are on the increase in the Western world, due in many cases to Insulin Resistance, which causes an imbalance in glucose and insulin levels in the blood stream. In turn, this imbalance often leads to obesity, a root cause of Pre-and Type 2 Diabetes. But research from Finland shows that switching to healthier habits can prevent or postpone both these forms of Diabetes.

The Finnish Diabetes Prevention Study1 included 522 overweight men and women between 40 and 65, who all had impaired glucose tolerance, an intermediate stage between normal blood glucose levels and Type 2 Diabetes. The participants were randomly divided into two groups, one designated as a control group and one as an intervention group.

At the beginning of the study, the control group was given general information about weight loss, good eating habits and the benefits of regular exercise. Participants were periodically reminded of the information.

The more closely-supervised intervention group received information in greater detail on the same subjects and members were individually coached at regular intervals on how to take up healthier habits like exercise and eating a balanced diet. In particular, they learned strategies for achieving specific goals, including a weight reduction target of 5% or more via a moderate exercise program of at least 30 minutes a day.

The resulting differences in the two groups were dramatic. Members of the intervention group lost an average of 9 1/4 lbs each and were almost 60% less likely to develop Pre-and Type 2 Diabetes than participants in the other group. Researchers found that just four hours of exercise a week lowered the risk of developing Type 2 Diabetes. Even postponing the onset of this disorder is highly advantageous because Type 2 Diabetes can damage the heart, kidneys, nerves and eyes.

Researchers discovered that, in the final analysis, it seems to come down to the individual’s determination to avoid illness. Some members of the intervention group didn’t achieve any of the study’s goals, even with coaching, while some individuals in the loosely-supervised control group achieved all the goals without individual coaching. The closer individuals came to achieving the study goals, the less likely they were to develop Type 2 Diabetes, no matter which group they were in.

Source : 1 Tuomilehto J et al. Prevention of Type 2 Diabetes Mellitus by changes in lifestyle among subjects with impaired glucose tolerance. New England Journal of Medicine 2001; 344(18): 1343-50

  Weight Loss: Myth or Fact?
Myth: Once I Change to a Healthier Diet, Missing my Favorite Food will be Agony

Fact: Within one week, your tastes will start to change in favor of your new healthier choices. Eating sugar encourages more sugar-eating. If you have stabilized your blood sugar and are avoiding carbohydrates, you will soon realize you are no longer dreaming of sweet-tasting food. Instead, your tastes will run more to low carb meals that have much healthier contents like vegetables and fruit. Visible signs of losing weight will also be a great morale-booster.

Dr Mary Shackelton - Medical Director for Insulite Laboratories
Q. I am overweight and plan to get pregnant. Will the extra pounds that I am carrying affect the health of my future baby?

A. Obesity is on the rise across all ages of the population, particularly amongst adolescents. According to the March of Dimes, obesity among women of childbearing age is at a “crisis level”.

There are numerous increased health risks for both the mother and the fetus if the mother is overweight or obese during pregnancy. Pregnant obese women are at risk for pre-eclampsia, hypertension, gestational diabetes, cesarean delivery and post partum infection, while the fetus is at risk for birth trauma, late fetal death and neural tube defects.1

Research confirms that risks to the infant and developing child are higher for mothers who were obese during their pregnancy. One study found that the risk of developing Metabolic Syndrome was increased when children were exposed to maternal obesity2. These children are more likely to be larger at birth which poses additional risks. Additionally, higher birth weight predicted increased risk of being overweight in adolescence.3

One study showed that women, whose mothers were obese during pregnancy, subsequently struggled as adults with weight problems, high blood pressure, blood sugar abnormalities and a higher Body Mass Index.4

It is important for any woman who is considering conceiving to first attempt safe and healthy weight loss through diet, exercise and nutrient supplementation. In fact, the ability to become pregnant is enhanced, as weight loss often allows for a normalization of sex hormones. Weight loss tips include reducing insulin and glucose levels by avoiding refined carbohydrates (e.g. pasta, cookies, breads, bagels, crackers, chips, soda and sugar) and increasing the intake of protein and green vegetables. Nutrient supplements that can decrease glucose and insulin levels include chromium picolinate and vanadium.

Given the current epidemic of obesity and the implications on the health of our culture, these findings highlight the importance of controlling maternal obesity not only for the health of the infant and later adolescent but also to interrupt the cycle of obesity, Insulin Resistance and the health and social consequences for subsequent generations. (See also Intelligence Report)

Sources: 1 Atalah, E., Castro R., Maternal obesity and reproductive risk. Rev Med Chil. 2004 Aug;132(8):923-30.

2 Boney CM, Verma A, Tucker R, Vohr BR, Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus, Pediatrics. 2005 Mar;115(3):e290-6

3 Gillman MW, Rifas-Shiman S, Berkey CS, Field AE, Colditz GA, Maternal gestational diabetes, birth weight, and adolescent obesity. Pediatrics. 2003 Mar;111(3):e221-6.

4 Vohr BR, McGarvey ST, Tucker R. Effects of maternal gestational diabetes on offspring adiposity at 4-7 years of age. Diabetes Care. 1999 Aug;22(8):1284-91

“I cannot believe the difference the Insulite System has made in how I feel. My appetite has changed tremendously. I do not crave carbs and sugar and my appetite is somewhat diminished.”

- P.R.
  Bakersfield, CA

Insulite Laboratories would like to share other experiences like this one to inspire our many clients on the same path. Tell us your story and we will use it in a future issue of this newsletter, as well as on web sites and affiliate sites.

If you are uncomfortable with us publishing your name, we are quite happy to use your initials to preserve your anonymity. Please email us at

Have You Been Diagnosed with Metabolic Syndrome?

If You Have, We’re Glad That You Have Found Us.

We’re Here to Support You.

Insulite Laboratories is committed to reversing Metabolic Syndrome by giving you a better understanding of your condition and its underlying cause, Insulin Resistance.

Supporting you in any way we can is central to our philosophy.

Soon to be introduced, the Insulite MetaX System has been scientifically-formulated to reverse Insulin Resistance. It contains an ingredient called Meta-OmegaX which is targeted specifically at the symptoms of Metabolic Syndrome.

Our web site and future editions of
“Viewpoints” will keep you updated.

New Health Guides to Supermarkets


More food packaging is set to feature a new health guide. The Glycemic Index (GI) is proving so popular among people intent on healthy eating that food manufacturers think an increasing number of customers regard it as a fresh way to lose weight by controlling carbohydrate intake. So they plan to add a GI listing to more food products.

The GI was originally designed to help people with Type 2 Diabetes to manage their blood sugar. It ranks carbs according to how fast they are digested and raise blood sugar levels.

High glycemic carbs like refined flours found in white bread are digested quickly, which is bad for you because it causes a spike in blood sugar followed by a crash. Insulin levels also rise accordingly and you feel hungry again more quickly. Low glycemic carbs like whole grains have greater benefit because they are digested more slowly and sustain energy, helping to make you feel full longer.

Research suggests that blood sugar and insulin spikes over a long term can increase the risk of Insulin Resistance. This disorder can, in turn, lead to obesity and the development of Pre- and Type 2 Diabetes, as well as PCOS, a leading cause of infertility in women, and the cluster of Cardiovascular Diseases known as Metabolic Syndrome.

Slow carbs include beans, brown rice, lentils and dried apricots. Fast carbs like potatoes and sports drinks can be beneficial during exercise for quick energy and also to replenish stores of glycogen (starch) after exercise.

Numerous factors can affect the GI of a food, including how the product is cooked and chewed, the protein, fat and fiber content and, with fruit, the ripeness (bananas with some green peel, for example, have a lower GI than those with brown specks).

Foods are grouped by their GI number: less than 60 is low, 60-85 is moderate and greater than 85 is high. Three examples: asparagus (low - 15), taco shell (medium - 68) and instant rice (high - 95). Last year, 175 new products were marketed as "low glycemic" compared to 2 in 1999.

Food shouldn't be chosen on its GI rating alone and it's best to take into account overall nutritional value. The World Health Organization, which has given the thumbs-up to low-GI eating, agrees with this approach. Ice cream, for instance, has a lower GI rating than watermelon, even though the former is loaded with fat and sugar, while the latter is packed with vitamins A and C.

No-carb foods like meat and cheese have a zero GI , regardless of how fat or salt-laden they might be. Nutritionists say it's best to chose leaner cuts of meat and lower fat dairy foods as part of a healthy diet.
Shoot for the Moon
“When you shoot for the moon and come up short, you still end up among the stars.”
  - Les Brown
Every effort brings rewards.


Stay CoolSTAYING COOL WITHOUT PILING ON THE POUNDS. With the temperature soaring, there's nothing like an old-fashioned ice cream cone for cooling you down. Unfortunately, high-carbohydrate ice cream isn't an ideal choice if you're watching your weight.

But there are plenty of alternatives for staying cool without wrecking your diet. Stores now stock a wide variety of low-calorie frozen treats, ranging from low-carb ice cream to fruit juice bars and lemonade with Splenda or Stevia, instead of sugar. And with a little creativity, you can stock your freezer with healthy, homemade treats to get you through the long hot days of summer.

Low-carb and low-fat ice creams tend to be pricier than the plain old-fashioned variety. But that doesn't necessarily mean that your pocketbook has to suffer. Instead, try these healthy, inexpensive and cooling ideas:

  • Frozen unsweetened fruits like blueberries and strawberries are not only great antioxidants but they are also taste refreshing by themselves or topped with a little whole fat yogurt. Remember it is not the fat that makes us fat but the sugar and carbs - the more we eat real fat, the less we will be hungry, with everything in moderation, of course. For example, if you ate a wheel of brie cheese daily with no carbs in it, you would probably not lose weight.

  • Make fruit and cream pops by filling small, Dixie-style cups or a Popsicle mould with a blend of fruit and low-fat vanilla yogurt.

  • Slice and freeze several bananas, 12 slices to a bag, and enjoy a cold creamy treat.

  • Mix a scoop of low-fat vanilla ice cream with diet root beer to make a delicious, diet-friendly root beer float.

  • Place a tablespoon of chocolate chips in the freezer for ten minutes before eating. The chips are only about 70 calories and offer a quick, cool chocolate fix.

Don't forget that it's OK to treat yourself to a small portion of old-fashioned ice cream now and again. But remember to "get back on the wagon" the next day.

Salmon has Omega-3 Fatty AcidsThe health benefits of omega-3 fatty acids are now well-established. But what exactly are they and how do they help the body?

Omega-3 fatty acids are fundamental molecules in the structure and activity of the membranes of all cells throughout the body. They also have highly specialized functions of a neurological nature, especially concerning the brain and the retina of the eye, and are vital for the formation of new tissue leading to development and growth.

Known to be essential for brain and vision development during the last three months of pregnancy, omega-3 fatty acids continue to play a major health role at every stage of life through the prevention or management of disorders such as Cardiovascular Disease.

A wealth of research has shown that omega-3 can reduce levels of triglycerides, the fat-storing substances carried through the bloodstream for energy, and lower the risk of arrhythmia, which can lead to sudden cardiac arrest. Omega-3 can also slightly lower blood pressure, as well as reducing the growth rate of atherosclerosis plaque, which blocks arteries.

Fish are a good source of omega-3 fatty acids and varieties like mackerel, lake trout, herring, sardines, albacore tuna and salmon are rich in the key constituents eicosapentaenoic acid (EPA) and dicosahexaenoic acid (DHA). Levels of mercury in fish should certainly be considered, though sitting down to a fish dish once a week shouldn't present any health risks.

However, many people don't like eating fish, so Part Two in next month's Newsletter will look at how to maintain omega-3 intake by taking supplements.

Insulite Laboratories is Here for You
You are well on the way to reversing your Insulin Resistance and preventing its related conditions such as PCOS (Polycystic Ovarian Syndrome), Metabolic Syndrome (Syndrome X) and Pre-Diabetes. You are also taking important steps to achieving your desired weight loss goal and the healthy lifestyle you deserve.

Remember that persistence is crucial.

We at Insulite Laboratories are committed to your success and your well being. We're here to help you.

Please contact us with any questions or to order the Insulite System or the Insulite PCOS System at

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DISCLAIMER: The information contained in this newsletter is for the sole purpose of being informative. This information is not and should not be used or relied upon as medical advice. Always seek the advice of your physician, nurse or other qualified health care provider before you undergo any treatment, take any medication, supplements or other nutritional support, or for answers to any questions you may have regarding a medical condition.

Nothing contained in or provided through this newsletter is intended to be or is to be used or relied upon for medical diagnosis or treatment. Your use of our newsletter opportunity is subject to certain terms and conditions including, but not limited to, the fact that you have not been seen, evaluated or diagnosed by a qualified medical/health care provider through the use of our newsletter service.

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