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VIEWPOINTS:
HEALING NEWS FROM INSULITE LABORATORIES
January 2006
IN THIS ISSUE: Insulite Laboritories

Welcome to the twenty-second edition of Viewpoints, our monthly e-newsletter.

We at Insulite Laboratories never underestimate the discipline and effort required to lose weight and keep it off. So we're always happy to tell you about weight-loss tips that make it little easier for you to accomplish your goals of better health and a greater sense of well-being.

People who keep a daily food record, for instance, usually lose more weight because they eat less while keeping track of their consumption. It acts as a constant reminder of what they're trying to achieve.

One diet doesn't fit all. Experiment with a variety of healthy eating habits to see which one works for you.

In the first thee months of their plan, dieters tend to achieve two-thirds of the weight-loss that they're ultimately going to achieve. The remaining third is lost in the second three months, after which weight-loss typically stops.

There may be several explanations which could help you guard against this development. People may be more conscientious about adhering to their plan early on because it hasn't become too dull or depriving. Another factor is the reality that weight loss slows because of reductions in the resting metabolic rate or the speed at which you burn energy.

Plus there are physiological reasons why it's difficult to lose more than 5-10% of body weight. Several hunger hormones adapt to weight loss and increase appetite as the body fights against your good intentions in effort to return to its normal weight. It all dates back to Pre-History when the body developed instinctual mechanisms and thought patterns to avoid starvation.

One way to overcome these hurdles is to vary your diet so it remains nutritious but doesn't become boringly repetitious. Read the healthy eating sections in newspapers and magazines and be on the constant look-out for fresh taste treats.

Another way is to moderate your ambitions. Most medical experts consider a 20-lb weight loss to be a success, though many dieters disagree and want to lose more. They see the weight they haven't shed rather than the pounds that they have lost.

One suggestion might be to lose 10% of your total weight and then maintain that level for three months. Then try to lose another 5-10%.

If the going gets tough, don't forget that we're here to help you achieve your goals of weight-loss, good health and well-being in any way we can.




“Living a healthy lifestyle will only deprive you of poor health, lethargy and fat.”

- Jill Johnson

Open up new horizons by staying fit.
Live Healthy

INTELLIGENCE REPORT

Intelligence Report
GENE LINKS OBESITY TO PRE-DIABETES

Hopes are growing for a new diagnostic test for Pre-Diabetes following the discovery of a DNA gene linking the condition to obesity.

Faulty versions of the gene, called ENPP1, disrupt the way the body stores energy and handles blood glucose by blocking insulin in a form of the condition called Insulin Resistance. This latter disorder causes an imbalance of glucose and insulin in the blood stream and can lead to excessive weight gain, which, in turn, may result in reversible Pre- Diabetes. Children with this defective gene have been known to become obese as early as five years old.

Researchers in a joint British and French team believe that spotting the problem early and intervening could save lives. This is because obesity and Pre-Diabetes leading to the irreversible, full-blown Type 2 variety increase the risk of developing other serious disorders such as the cluster of cardiovascular diseases called Metabolic Syndrome (Syndrome X).

While sedentary lifestyles and poor diets play a key role in the onset of obesity and the metabolic problems that can lead to Diabetes, the authors of this study say some people are genetically prone as well. As many as 20% of white people and 50% of the black community may be vulnerable because of their genes. (1)

Research leader Dr. Phillipe Froguel said the combination of regular exercise and a balanced, nutritional diet were imperative if these people were to avoid serious health problems later in life.

Researchers from London's Imperial College and the Institut Pasteur in Lille looked at French families with a strong history of Diabetes and obesity, comparing them with families that did not. When they compared the genes of 1,225 children who were obese or overweight at ages between five and 11 with 1,205 children of normal weight, they found an obvious pattern - many of the obese children possessed faulty versions of ENPP1.

Looking at adults in the families, they found a similar link between the ENPP1 variants and obesity, as well as between the gene variants and early warning signs of Diabetes. ENPP1 was also linked to full-blown Type 2 Diabetes in the adults.

Dr. Froguel said: "What is extremely worrying is the children who had these mutations developed obesity at an early age - five to six - and Diabetes occurred in middle age."

He added that, although the discovery would not lead to a 'magic pill' for curing obesity and Pre- and Type 2 Diabetes, it could help in identifying groups and individuals at increased risk.

"If we can identify those at risk at an earlier age, it may be possible to take preventative measures earlier on, and reduce the burden of ill health caused by obesity in later life," said Dr. Froguel.

While it was technically possible to screen people for the ENPP1 variants, he did not think it was the most appropriate route to tackle the problem. Instead, he said it would be better to introduce public health measures such as encouraging food and drinks manufacturers to lower the sugar and fat content in food and encouraging families to take more exercise.

The researchers did not assess how much the genes were to blame for weight gain and metabolic problems as opposed to poor diet or lack of exercise. However, Dr Froguel said those with a family history of Diabetes and obesity should be particularly vigilant with regards to lifestyle.

A root cause of obesity is often Insulin Resistance, which creates an imbalance in glucose and insulin levels in the blood stream. Insulin receptor sites on the cell wall act as "a key in a lock," allowing glucose to pass through the wall and be converted to energy. Insulin Resistance vastly reduces the number of these receptor sites, causing glucose to "bounce" off the cell wall and then free-float in the blood stream to the liver.

Once there, the glucose, or sugar, is converted into fat and stored via the blood stream throughout the body, often leading to obesity. Insulin Resistance also causes excess insulin in the blood stream which greatly increases the risk of developing Pre-Diabetes.

Insulin Resistance-linked obesity is also a key factor in the onset of the hormonal imbalance known as Polycystic Ovarian Syndrome (PCOS), a leading cause of female infertility.

(1)Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and Type 2 Diabetes,
Nature Genetics 37, 863-867, 8/1/05


Click here to learn about a system that helps reverse
Insulin Resistance and Pre-Diabetes.

NEW RESEARCH

New Research

HIGH GLUCOSE LEVELS CONTRIBUTE TO HEART ATTACKS AND IMPEDE RECOVERY

Victims of heart attacks have been found to have high blood glucose levels upon admission to the hospital, even if they haven't been diagnosed with Pre- or Type 2 Diabetes.

In an effort to understand the link between high blood glucose, heart attacks and recovery rates, researchers studied 779 patients at a teaching hospital in Estonia in Eastern Europe over a two-year period (1). They also measured the death rate of these people within 180 days after a heart attack.

The researchers reviewed medical records to gather information about high glucose levels, which can affect blood flow through the arteries, and the medical treatment administered for the patients' heart attacks.

More than 10% of patients (109 of 799) had no history of Diabetes but still had high glucose levels. Of those with a history of Diabetes, 84 out of 779 had higher than normal glucose levels.

The worst outcomes after a heart attack were seen among people with no history of Diabetes but high glucose levels when they were admitted to the hospital. These patients were more likely to have cardiac arrest (no breathing or heartbeat) before reaching the hospital. If they survived, they were nearly 4.5 times more likely to die within 180 days of having a heart attack.

The patients' history of Diabetes was based on reading medical records. Specific blood tests to diagnose Pre- and Type 2 Diabetes weren't done for these heart attack victims, so some of them could have had one form of Diabetes or the other without patients or doctors realizing it.

High levels of glucose are a classic symptom of Insulin Resistance-linked Pre-Diabetes, which is diagnosed when a patient's glucose level is higher than normal but not yet in the Type 2 Diabetes range. Pre-Diabetes is a reversible condition. But if neglected, it may lead to Type 2 Diabetes, which can only be managed for the rest of a person's life and may require daily injections of insulin.

Insulin Resistance is an insidious but reversible disorder that can cause Pre-Diabetes by creating an imbalance of blood glucose and insulin leading to weight gain and obesity.

One limitation of the Estonia study concerned the fact that it consisted of a review of medical records, whereas a clinical trial might reach different conclusions. Another limitation was that the information was drawn from one hospital, which might treat heart attacks in subtle ways that could affect the outcome, compared to another hospital.

But after taking into account these considerations, the study concluded that it does appear that high blood glucose levels are a sign that a patient is more likely to die after receiving hospital treatment following a heart attack.


(1)The association between hyperglycemia on admission and 180-day mortality in acute myocardial infarction patients with and without diabetes, by T. Ainla and colleagues.
Diabetic Medicine Vol 22, Issue 10:1321–1324, 2005.



WEIGHT LOSS: MYTH OR FACT?
  Weight Loss: Myth or Fact?
Myth: The Healthiest Diet is Fat-Free

Fact: Fat in a diet tends to have a negative image and it's easy to become fat phobic. But you need some fat for your body to function properly, not least because it helps transport vitamins A, D, E and K to tissues throughout your body.

And don't forget that, as well helping to regulate your hormones and keep your nervous system humming, dietary fat also enhances the flavor of foods and adds immeasurably to the pleasure of healthy eating.

The general recommendation of nutritionists is to keep your fat intake from items such as fish and skinless poultry like chicken to somewhere between 20-30% of your total daily calories. Rest assured that fat in moderation is an important part of everyday healthy eating.


CONSULT DR. MARY
Dr Mary Shackelton - Medical Director for Insulite Laboratories
Q. Why is protein important?
 

A. A growing body of scientific evidence suggest that lean protein not only provides nutrition but also plays a key role in helping you to feel full for a longer period of time.

It could explain why some dieters are more successful at losing weight on programs that include moderate amounts of fish, chicken, lean meat, bean, nuts and other protein-rich foods.

Researchers are now trying to understand how protein works to increase the feeling of fullness. A Government-funded study has begun following dieters for two years on different eating regimens that vary the daily proportions of proteins, fats and carbs.

One theory is that consuming protein does not trigger the secretion of insulin by the pancreas, with the result that the impact on blood sugar levels is minimal, compared to eating carbohydrates. More stable blood sugar levels decrease hunger and cravings between meals.

There may also psychological reasons for protein's satiety value. Understandably, many people tend to think meals are more substantial if they contain meat or other protein.

In the past, some in the medical community have had reservations about the health benefits of a high intake of protein. But, for now at least, the Institute of Medicine has concluded that there is no clear evidence that high protein intake increases the risk of obesity, coronary artery disease, kidney stones and osteoporosis.


“I have been using the Insulite System now for approximately six months. I always had major problems with sugar and carbohydrate cravings causing an eating disorder. Even though I learned to control the cravings, it has always been a real struggle. My blood sugar has been up and down like a yo-yo, causing my weight to do the same thing.

"I have used all sort of products, including Ephedra, which I found really bad. But when I started using the Insulite System and paying more attention to the diet plan it offers, my cravings vanished almost overnight. I simply could not believe that I was no longer plagued by them.

"I feel 100% better and have tons of energy. I sleep a lot better also. I cannot recommend Insulite highly enough. I have recommended this product to friends and they are having the same excellent results. It is such a relief to have finally found a way to keep my blood sugar levels under control.
Thank you Insulite Labs!!!”
 
 

- DIANE WILSON
  TRYON, N.C.

 
Insulite Laboratories would like to share other experiences like this one to inspire our many clients on the same path. Tell us your story and we will use it in a future issue of this newsletter, as well as on web sites and affiliate sites.

If you are uncomfortable with us publishing your full name, we are quite happy to use your initials or first name to preserve your anonymity. We do ask that you include the name of your hometown and state or, in the case of our numerous clients outside the U.S.A., your country. Please email us at testimonials@insulitelabs.com


Have You Been Diagnosed with Pre-Diabetes?

If You Have, We're Glad That You Have Found Us.

We're Here to Support You.


Pre-DiabetX ProductInsulite Laboratories is committed to reversing Pre-Diabetes by giving you a better understanding of your condition and its underlying cause, Insulin Resistance.

So we are very pleased to announce the introduction of the Insulite Pre-Diabetes System, which has been scientifically-formulated to help reverse Insulin Resistance, obesity and Pre-Diabetes. All three disorders are linked to each other.

If left unchecked, Pre-Diabetes can lead to Type 2 Diabetes, which can only be managed for the rest of a person's life and may require daily insulin. Type 2 Diabetes is a greatly increased risk factor for kidney disease, blindness and amputation, as well as the cluster of cardiovascular diseases called Metabolic Syndrome.

The Insulite Pre-Diabetes System contains a scientifically-designed product called Pre-DiabetX, which directly lowers elevated levels of blood glucose caused by Insulin Resistance-connected obesity.

For more information, please go to pre-diabetes.insulitelabs.com



DID YOU KNOW?
Did You Know?

CIRRHOSIS OF THE LIVER IS STRIKING OVERWEIGHT TEENS

Liver diseases, including cirrhosis, are increasingly being seen in overweight teenagers.

Cirrhosis, which is irreparable liver damage, is commonly linked with alcohol misuse. But it can also be caused by a fatty diet which includes an excessive intake of fast food and sugar-laden drinks.

Dr Giorgina Mieli-Vergani, a specialist at King's College Hospital in London, has warned that teenagers with liver problems may need transplants in later life.

She said she had seen one 15-year-old who was very overweight and suffering from cirrhosis and other liver problems linked to obesity.

In cirrhosis, which occurs during the late stages of various liver disorders, normal tissue is destroyed and replaced by fibrous scar tissue. This permanent damage prevents the liver from performing its normal functions.

However, Dr Mieli-Vergani said this was the severe end of the spectrum and the more common problem she saw was non-alcoholic steato-hepatitis (NASH). She said that 10 years ago she saw around one child every two years with NASH. However, the frequency has now risen to between six and ten in the same time period.

NASH increases the risk of having further liver problems. Both cirrhosis and NASH could increase the risk of affected teenagers eventually requiring a liver transplant if they do not change their habits by eating a healthier diet and getting regular exercise.

Dr Mieli-Vergani said that the U.S. was seeing the most cases of NASH, but warned the U.K. was probably the "worst country in Europe" for the disease.

She said this was largely due to the high-fat, high sugar diet that many children consume. Excess fat in liver cells can cause them to expand, leading to inflammation and scarring.

 
Doctors
“The doctor of the future will give no medicine and, instead, will interest patients in the care of the human frame, in diet and in the cause and prevention of disease.”
  - Thomas Edison
Take control of your future by
improving your health.


INSULITE LIFESTYLE: TIPS

Supermarket

CONSUMERS GET NEW INFORMATION ON HEALTHY EATING

A trip to the supermarket now offers fresh insight into the potentially harmful content of food products. Since January 1, new federal rules for packaged foods make it mandatory to list ingredients that could contribute to heart disease and serious allergies.

From now on, labels will show the amount of heart-unhealthy trans-fat as well as the presence of eight major potential allergens. The Food and Drug Administration (FDA) defines a major allergen as an ingredient that contains protein derived from milk, eggs, fish, crustacean shellfish (such as crab, lobster or shrimp), tree nuts (such as almonds, pecans or walnuts), wheat, peanuts and soybeans. Together, these allergens make up 90% of all food allergies in the U.S.

Nutritionists say the prospect of having to list trans-fat has forced food manufacturers to stop using the product's primary source, namely hydrogenated oils. Vegetable oil is hydrogenated when the liquid oil is heated in the presence of a catalyst, often a metal like nickel or platinum, while hydrogen is bubbled through it. It is used in processed foods because, chemically, it is more like animal fat and less likely to go rancid. That makes it perfect for frying and industrial baking.

The labeling change is based on scientific evidence that trans-fat is associated with an increased risk of Cardiovascular Disease. The ruling was announced in advance in July 2003, so food manufacturers have been scrambling for nearly the last three years to reformulate products to give them a better " fat profile." Trans-fats have been reduced or eliminated, while saturated fat content, which is found primarily in animal products, has been lowered and healthier polyunsaturated fat has been increased.

There is still a loophole because restaurants are not required to list trans-fat levels in their menus. But nutritionists expect America to eventually follow the lead of Denmark, which, has, in effect, banned the use of hydrogenated oil.

Many of the allergens were already listed voluntarily but often under confusing technical names like casein and whey, which are both milk products. The allergens are now shown in plain English wording so parents and children alike can understand them. The FDA estimates that 2-5% of American children have food allergies.

More label changes are in the pipeline. The FDA is considering new rules to require more realistic calorie counts, including giving calories for the entire package, not just a single serving, as well as printing calorie numbers in larger type.

The agency is also in the process of re-computing the dietary values of vitamins and other nutrients, some of which have not been updated since 1968.



Men and HealthIt's never too late for men to make a New Year's resolution to start getting regular check-ups.

Women tend to be sensible about discussing medical matters with friends and consulting their doctor regularly, whereas many men are notoriously reluctant to do the same.

"Men's avoidance of health care begins at a young age when they are encouraged not to cry after hurting themselves," says Dr. Jean Bonhomme of the Men's Health Network. "By the time they are adults, they have learned not to seek medical care."

But preventative action can make the difference between life and death, so men should shake off their reluctance to seek medical advice and examinations.

Starting at the age of 35, cholesterol levels should be checked every couple of years, along with blood pressure. If you smoke, have reversible Pre-Diabetes or irreversible Type 2 Diabetes or a family history of heart disease, start at the age of 20. Regular blood sugar tests are advisable at any age to avoid the various forms of Diabetes.

Doctors recommend colorectal health checks starting at 50, beginning with annual fecal occult blood tests, plus a sigmoidoscopy (an inspection of the large intestine via the colon) every five years, double barium contrast enema
at the same interval and a colonoscopy (to search for potential abnormalities like cancer in the colon) every ten years.

African-Americans are especially prone to prostate cancer and should begin having the Prostate Specific Antigen (PSA) blood test at age 45. Other men should start at 50. Have the test every couple of years afterwards.

Monthly self testicular and breast examinations are recommended by the Men's Health Network. Seek help from your doctor if you regularly feel depressed and keep a close watch on both your weight and any skin conditions like moles.

Keeping as fit as possible is the only sensible course of action. And that's as true for men as it is for women!




Insulite Laboratories is Here for You
You are well on the way to reversing your Insulin Resistance and preventing its related conditions such as PCOS (Polycystic Ovarian Syndrome), Metabolic Syndrome (Syndrome X) and Pre-Diabetes. You are also taking important steps to achieving your desired weight loss goal and the healthy lifestyle you deserve.

Remember that persistence is crucial.

We at Insulite Laboratories are committed to your success and your well being. We're here to help you.

Please contact us with any questions or to order the Insulite System, Insulite PCOS System, Insulite MetaX System, or the new  Insulite Pre-Diabetes System at info@insulitelabs.com


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DISCLAIMER: The information contained in this newsletter is for the sole purpose of being informative. This information is not and should not be used or relied upon as medical advice. Always seek the advice of your physician, nurse or other qualified health care provider before you undergo any treatment, take any medication, supplements or other nutritional support, or for answers to any questions you may have regarding a medical condition.

Nothing contained in or provided through this newsletter is intended to be or is to be used or relied upon for medical diagnosis or treatment. Your use of our newsletter opportunity is subject to certain terms and conditions including, but not limited to, the fact that you have not been seen, evaluated or diagnosed by a qualified medical/health care provider through the use of our newsletter service.

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