Welcome to the twenty-second edition of Viewpoints, our monthly e-newsletter.
We at Insulite Laboratories never underestimate the discipline and effort
required to lose weight and keep it off. So we're always happy to tell you about
weight-loss tips that make it little easier for you to accomplish your goals of
better health and a greater sense of well-being.
People who keep a daily food record, for instance, usually lose more weight
because they eat less while keeping track of their consumption. It acts as a
constant reminder of what they're trying to achieve.
One diet doesn't fit all. Experiment with a variety of healthy eating habits to
see which one works for you.
In the first thee months of their plan, dieters tend to achieve two-thirds of
the weight-loss that they're ultimately going to achieve. The remaining third is
lost in the second three months, after which weight-loss typically stops.
There may be several explanations which could help you guard against this
development. People may be more conscientious about adhering to their plan early
on because it hasn't become too dull or depriving. Another factor is the reality
that weight loss slows because of reductions in the resting metabolic rate or
the speed at which you burn energy.
Plus there are physiological reasons why it's difficult to lose more than 5-10%
of body weight. Several hunger hormones adapt to weight loss and increase
appetite as the body fights against your good intentions in effort to return to
its normal weight. It all dates back to Pre-History when the body developed
instinctual mechanisms and thought patterns to avoid starvation.
One way to overcome these hurdles is to vary your diet so it remains nutritious
but doesn't become boringly repetitious. Read the healthy eating sections in
newspapers and magazines and be on the constant look-out for fresh taste treats.
Another way is to moderate your ambitions. Most medical experts consider a 20-lb
weight loss to be a success, though many dieters disagree and want to lose more.
They see the weight they haven't shed rather than the pounds that they have
One suggestion might be to lose 10% of your total weight and then maintain that
level for three months. Then try to lose another 5-10%.
If the going gets tough, don't forget that we're here to help you achieve your
goals of weight-loss, good health and well-being in any way we can.
“Living a healthy lifestyle will only deprive you of poor
health, lethargy and fat.”
Open up new horizons by staying fit.
GENE LINKS OBESITY TO PRE-DIABETES
Hopes are growing for a new diagnostic test for Pre-Diabetes following the
discovery of a DNA gene linking the condition to obesity.
(1)Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and Type 2 Diabetes,
Faulty versions of the gene, called ENPP1, disrupt the way the body stores
energy and handles blood glucose by blocking insulin in a form of the condition
called Insulin Resistance. This latter disorder causes an imbalance of glucose
and insulin in the blood stream and can lead to excessive weight gain, which, in
turn, may result in reversible Pre- Diabetes. Children with this defective gene
have been known to become obese as early as five years old.
Researchers in a joint British and French team believe that spotting the problem
early and intervening could save lives. This is because obesity and Pre-Diabetes
leading to the irreversible, full-blown Type 2 variety increase the risk of
developing other serious disorders such as the cluster of cardiovascular
diseases called Metabolic Syndrome (Syndrome X).
While sedentary lifestyles and poor diets play a key role in the onset of
obesity and the metabolic problems that can lead to Diabetes, the authors of
this study say some people are genetically prone as well. As many as 20% of
white people and 50% of the black community may be vulnerable because of their
Research leader Dr. Phillipe Froguel said the combination of regular exercise
and a balanced, nutritional diet were imperative if these people were to avoid
serious health problems later in life.
Researchers from London's Imperial College and the Institut Pasteur in Lille
looked at French families with a strong history of Diabetes and obesity,
comparing them with families that did not. When they compared the genes of 1,225
children who were obese or overweight at ages between five and 11 with
1,205 children of normal weight, they found an obvious pattern - many of the
obese children possessed faulty versions of ENPP1.
Looking at adults in the families, they found a similar link between the ENPP1
variants and obesity, as well as between the gene variants and early warning
signs of Diabetes. ENPP1 was also linked to full-blown Type 2 Diabetes in the
Dr. Froguel said: "What is extremely worrying is the children who had these
mutations developed obesity at an early age - five to six - and Diabetes
occurred in middle age."
He added that, although the discovery would not lead to a 'magic pill' for
curing obesity and Pre- and Type 2 Diabetes, it could help in identifying groups and
individuals at increased risk.
"If we can identify those at risk at an earlier age, it may be possible to take
preventative measures earlier on, and reduce the burden of ill health caused by
obesity in later life," said Dr. Froguel.
While it was technically possible to screen people for the ENPP1 variants, he
did not think it was the most appropriate route to tackle the problem. Instead,
he said it would be better to introduce public health measures such as
encouraging food and drinks manufacturers to lower the sugar and fat content in
food and encouraging families to take more exercise.
The researchers did not assess how much the genes were to blame for weight gain
and metabolic problems as opposed to poor diet or lack of exercise. However, Dr
Froguel said those with a family history of Diabetes and obesity should be
particularly vigilant with regards to lifestyle.
A root cause of obesity is often Insulin Resistance, which creates an imbalance
in glucose and insulin levels in the blood stream. Insulin receptor sites on the
cell wall act as "a key in a lock," allowing glucose to pass through the wall
and be converted to energy. Insulin Resistance vastly reduces the number of
these receptor sites, causing glucose to "bounce" off the cell wall and then
free-float in the blood stream to the liver.
Once there, the glucose, or sugar, is converted into fat and stored via the
blood stream throughout the body, often leading to obesity. Insulin Resistance
also causes excess insulin in the blood stream which greatly increases the risk
of developing Pre-Diabetes.
Insulin Resistance-linked obesity is also a key factor in the onset of the
hormonal imbalance known as Polycystic Ovarian Syndrome (PCOS), a leading cause
of female infertility.
Nature Genetics 37, 863-867, 8/1/05
Click here to learn about a system that helps reverse
Insulin Resistance and Pre-Diabetes.
HIGH GLUCOSE LEVELS CONTRIBUTE TO HEART ATTACKS AND IMPEDE RECOVERY
Victims of heart attacks have been found to have high blood glucose
levels upon admission to the hospital, even if they haven't been diagnosed with
Pre- or Type 2 Diabetes.
In an effort to understand the link between high blood glucose, heart attacks
and recovery rates, researchers studied 779 patients at a teaching hospital in
Estonia in Eastern Europe over a two-year period (1). They also measured the
death rate of these people within 180 days after a heart attack.
The researchers reviewed medical records to gather information about high
glucose levels, which can affect blood flow through the arteries, and the
medical treatment administered for the patients' heart attacks.
More than 10% of patients (109 of 799) had no history of Diabetes but still had
high glucose levels. Of those with a history of Diabetes, 84 out of 779 had
higher than normal glucose levels.
The worst outcomes after a heart attack were seen among people with no history
of Diabetes but high glucose levels when they were admitted to the hospital.
These patients were more likely to have cardiac arrest (no breathing or
heartbeat) before reaching the hospital. If they survived, they were nearly 4.5
times more likely to die within 180 days of having a heart attack.
The patients' history of Diabetes was based on reading medical records. Specific
blood tests to diagnose Pre- and Type 2 Diabetes weren't done for these heart
attack victims, so some of them could have had one form of Diabetes or the other
without patients or doctors realizing it.
High levels of glucose are a classic symptom of Insulin Resistance-linked
Pre-Diabetes, which is diagnosed when a patient's glucose level is higher than
normal but not yet in the Type 2 Diabetes range. Pre-Diabetes is a reversible
condition. But if neglected, it may lead to Type 2 Diabetes, which can only be
managed for the rest of a person's life and may require daily injections of
Insulin Resistance is an insidious but reversible disorder that can cause
Pre-Diabetes by creating an imbalance of blood glucose and insulin leading to
weight gain and obesity.
One limitation of the Estonia study concerned the fact that it consisted of a
review of medical records, whereas a clinical trial might reach different
conclusions. Another limitation was that the information was drawn from one
hospital, which might treat heart attacks in subtle ways that could affect the
outcome, compared to another hospital.
But after taking into account these considerations, the study concluded that it
does appear that high blood glucose levels are a sign that a patient is more
likely to die after receiving hospital treatment following a heart attack.
between hyperglycemia on admission and 180-day mortality in acute myocardial
infarction patients with and without diabetes, by T. Ainla and colleagues.
Vol 22, Issue 10:1321–1324, 2005.
|WEIGHT LOSS: MYTH OR FACT?
Myth: The Healthiest Diet is Fat-Free
Fat in a diet tends to have a negative image and it's easy to become fat phobic.
But you need some fat for your body to function properly, not least because it
helps transport vitamins A, D, E and K to tissues throughout your body.
And don't forget that, as well helping to regulate your hormones and keep your
nervous system humming, dietary fat also enhances the flavor of foods and adds
immeasurably to the pleasure of healthy eating.
The general recommendation of nutritionists is to keep your fat intake from
items such as fish and skinless poultry like chicken to somewhere between 20-30%
of your total daily calories. Rest assured that fat in moderation is an
important part of everyday healthy eating.
|CONSULT DR. MARY
Q. Why is protein important?
A growing body of scientific evidence suggest that lean protein not only
provides nutrition but also plays a key role in helping you to feel full for a
longer period of time.
It could explain why some dieters are more successful at losing weight on
programs that include moderate amounts of fish, chicken, lean meat, bean, nuts
and other protein-rich foods.
Researchers are now trying to understand how protein works to increase the
feeling of fullness. A Government-funded study has begun following dieters for
two years on different eating regimens that vary the daily proportions of
proteins, fats and carbs.
One theory is that consuming protein does not trigger the secretion of insulin
by the pancreas, with the result that the impact on blood sugar levels is
minimal, compared to eating carbohydrates. More stable blood sugar levels
decrease hunger and cravings between meals.
There may also psychological reasons for protein's satiety value.
Understandably, many people tend to think meals are more substantial if they
contain meat or other protein.
In the past, some in the medical community have had reservations about the
health benefits of a high intake of protein. But, for now at least, the
Institute of Medicine has concluded that there is no clear evidence that high
protein intake increases the risk of obesity, coronary artery disease, kidney
stones and osteoporosis.
“I have been using the Insulite System now for approximately six months. I
always had major problems with sugar and carbohydrate cravings causing an eating
disorder. Even though I learned to control the cravings, it has always been a
real struggle. My blood sugar has been up and down like a yo-yo, causing my
weight to do the same thing.
"I have used all sort of products, including Ephedra, which I found really bad.
But when I started using the Insulite System and paying more attention to the
diet plan it offers, my cravings vanished almost overnight. I simply could not
believe that I was no longer plagued by them.
"I feel 100% better and have tons of energy. I sleep a lot better also. I cannot
recommend Insulite highly enough. I have recommended this product to friends and
they are having the same excellent results. It is such a relief to have finally
found a way to keep my blood sugar levels under control.
Thank you Insulite Labs!!!”
- DIANE WILSON
|Insulite Laboratories would like to share other
experiences like this one to inspire our many clients on the same path. Tell
us your story and we will use it in a future issue of this newsletter, as
well as on web sites and affiliate sites.|
If you are uncomfortable with us publishing your full name, we are quite
happy to use your initials or first name to preserve your anonymity. We do
ask that you include the name of your hometown and state or, in the case of
our numerous clients outside the U.S.A., your country. Please email us at
Been Diagnosed with Pre-Diabetes?
If You Have, We're Glad That You Have Found Us.
We're Here to Support You.
Insulite Laboratories is committed to reversing Pre-Diabetes by giving you a
better understanding of your condition and its underlying cause, Insulin
So we are very pleased to announce the introduction of the Insulite
Pre-Diabetes System, which has been scientifically-formulated to help
reverse Insulin Resistance, obesity and Pre-Diabetes. All three disorders
are linked to each other.
If left unchecked, Pre-Diabetes can lead to Type 2 Diabetes, which can only
be managed for the rest of a person's life and may require daily insulin. Type 2 Diabetes is a greatly increased risk factor for kidney
disease, blindness and amputation, as well as the cluster of cardiovascular
diseases called Metabolic Syndrome.
The Insulite Pre-Diabetes System contains a scientifically-designed product
called Pre-DiabetX, which directly lowers elevated levels of blood glucose
caused by Insulin Resistance-connected obesity.
For more information, please go to pre-diabetes.insulitelabs.com
|DID YOU KNOW?
CIRRHOSIS OF THE LIVER IS STRIKING OVERWEIGHT TEENS
Liver diseases, including cirrhosis, are increasingly being seen in
Cirrhosis, which is irreparable liver damage, is commonly linked with
alcohol misuse. But it can also be caused by a fatty diet which includes
an excessive intake of fast food and sugar-laden drinks.
Dr Giorgina Mieli-Vergani, a specialist at King's College Hospital in
London, has warned that teenagers with liver problems may need
transplants in later life.
She said she had seen one 15-year-old who was very overweight and
suffering from cirrhosis and other liver problems linked to obesity.
In cirrhosis, which occurs during the late stages of various liver
disorders, normal tissue is destroyed and replaced by fibrous scar
tissue. This permanent damage prevents the liver from performing its
However, Dr Mieli-Vergani said this was the severe end of the spectrum
and the more common problem she saw was non-alcoholic steato-hepatitis
(NASH). She said that 10 years ago she saw around one child every two
years with NASH. However, the frequency has now risen to between six and
ten in the same time period.
NASH increases the risk of having further liver problems. Both cirrhosis
and NASH could increase the risk of affected teenagers eventually
requiring a liver transplant if they do not change their habits by
eating a healthier diet and getting regular exercise.
Dr Mieli-Vergani said that the U.S. was seeing the most cases of NASH,
but warned the U.K. was probably the "worst country in Europe" for the
She said this was largely due to the high-fat, high sugar diet that many
children consume. Excess fat in liver cells can cause them to expand,
leading to inflammation and scarring.
“The doctor of the future will give no medicine and, instead,
will interest patients in the care of the human frame, in diet and
in the cause and prevention of disease.”
- Thomas Edison
Take control of your future by
INSULITE LIFESTYLE: TIPS
CONSUMERS GET NEW INFORMATION ON HEALTHY EATING
A trip to the supermarket now offers fresh insight into the potentially
harmful content of food products. Since January 1, new federal rules for
packaged foods make it mandatory to list ingredients that could contribute
to heart disease and serious allergies.
From now on, labels will show the amount of heart-unhealthy trans-fat as
well as the presence of eight major potential allergens. The Food and Drug
Administration (FDA) defines a major allergen as an ingredient that contains
protein derived from milk, eggs, fish, crustacean shellfish (such as crab,
lobster or shrimp), tree nuts (such as almonds, pecans or walnuts), wheat,
peanuts and soybeans. Together, these allergens make up 90% of all food
allergies in the U.S.
Nutritionists say the prospect of having to list trans-fat has forced food
manufacturers to stop using the product's primary source, namely
hydrogenated oils. Vegetable oil is hydrogenated when the liquid oil is
heated in the presence of a catalyst, often a metal like nickel or platinum,
while hydrogen is bubbled through it. It is used in processed foods because,
chemically, it is more like animal fat and less likely to go rancid. That
makes it perfect for frying and industrial baking.
The labeling change is based on scientific evidence that trans-fat is
associated with an increased risk of Cardiovascular Disease. The ruling was
announced in advance in July 2003, so food manufacturers have been
scrambling for nearly the last three years to reformulate products to give
them a better " fat profile." Trans-fats have been reduced or eliminated,
while saturated fat content, which is found primarily in animal products,
has been lowered and healthier polyunsaturated fat has been increased.
There is still a loophole because restaurants are not required to list
trans-fat levels in their menus. But nutritionists expect America to
eventually follow the lead of Denmark, which, has, in effect, banned the use
of hydrogenated oil.
Many of the allergens were already listed voluntarily but often under
confusing technical names like casein and whey, which are both milk
products. The allergens are now shown in plain English wording so parents and
children alike can understand them. The FDA estimates that 2-5% of American
children have food allergies.
More label changes are in the pipeline. The FDA is considering new rules to
require more realistic calorie counts, including giving calories for the
entire package, not just a single serving, as well as printing calorie
numbers in larger type.
The agency is also in the process of re-computing the dietary values of
vitamins and other nutrients, some of which have not been updated since
never too late for men to make a New Year's resolution to start getting
tend to be sensible about discussing medical matters with friends and
consulting their doctor regularly, whereas many men are notoriously
reluctant to do the same.
"Men's avoidance of health care begins at a young age when they are
encouraged not to cry after hurting themselves," says Dr. Jean Bonhomme of
the Men's Health Network. "By the time they are adults, they have learned
not to seek medical care."
But preventative action can make the difference between life and death, so
men should shake off their reluctance to seek medical advice and
Starting at the age of 35, cholesterol levels should be checked every couple
of years, along with blood pressure. If you smoke, have reversible
Pre-Diabetes or irreversible Type 2 Diabetes or a family history of heart
disease, start at the age of 20. Regular blood sugar tests are advisable at
any age to avoid the various forms of Diabetes.
Doctors recommend colorectal health checks starting at 50, beginning with
annual fecal occult blood tests, plus a sigmoidoscopy (an inspection of the
large intestine via the colon) every five years, double barium contrast
at the same interval and a colonoscopy (to search for potential
abnormalities like cancer in the colon) every ten years.
African-Americans are especially prone to prostate cancer and should begin
having the Prostate Specific Antigen (PSA) blood test at age 45. Other men
should start at 50. Have the test every couple of years afterwards.
Monthly self testicular and breast examinations are recommended by the Men's
Health Network. Seek help from your doctor if you regularly feel depressed
and keep a close watch on both your weight and any skin conditions like
Keeping as fit as possible is the only sensible course of action. And that's
as true for men as it is for women!
well on the way to reversing your Insulin Resistance and preventing its related
conditions such as PCOS (Polycystic Ovarian Syndrome), Metabolic Syndrome
(Syndrome X) and Pre-Diabetes. You are also taking important steps to achieving your desired weight loss goal
and the healthy lifestyle you deserve.
Remember that persistence is crucial.
We at Insulite Laboratories are
committed to your success and your well being. We're here to help you.
Please contact us with any questions or to order the Insulite System, Insulite PCOS
System, Insulite MetaX System, or the new Insulite Pre-Diabetes System at email@example.com
DISCLAIMER: The information contained in this newsletter is for the sole purpose of being informative.
This information is not and should not be used or relied upon as medical advice. Always seek the advice
of your physician, nurse or other qualified health care provider before you undergo any treatment, take
any medication, supplements or other nutritional support, or for answers to any questions you may have
regarding a medical condition.
Nothing contained in or provided through this newsletter is intended to be or is to be used or relied
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terms and conditions including, but not limited to, the fact that you have not been seen, evaluated or
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