Insulite Labs

Welcome to the fifth edition of Viewpoints, our monthly e-newsletter.

One of our major goals at Insulite Laboratories is to provide you with the key to well being through cutting edge research that impacts not only your weight loss regimen but, above all, your health. Now more than ever, it is apparent that losing weight and being well are inevitably linked.

In this issue, we focus on stress – an element in all of our lives – and a major contributor to Insulin Resistance, increasingly seen as the cause of many serious health risks including Metabolic Syndrome (Syndrome X), PCOS (Polycystic Ovarian Syndrome) Pre-Diabetes and excess weight gain.

Stressful situations often find us reaching for a hi-carb snack, a seemingly “comforting” fix. But here the link takes a negative turn. Recent research raises concerns about the relationship between hi-carb intake and breast cancer in women. Scientists suggest that carbs may increase cancer risk by quickly raising sugar in the blood and triggering surging insulin. This results in cell division leading to higher estrogen levels in the blood which can encourage cancer.

While most stress is unavoidable, we urge you to take steps to manage it as you would any other aspect of your life, like healthy eating. At Insulite Laboratories, your health is our greatest concern.


Walking on the Beach
“Little by little, one walks far.”

- Peruvian proverb

Small steps can lead to great things.

Hi Stress
Stress Takes Its Toll and Increases Insulin Resistance

We are all aware of the increased stress in our lives and evidence shows it is harmful to the body as well as the mind.

Stress comes in two forms: acute and chronic. Acute stress is a response to imminent danger. The chronic variety is caused by constant emotional or physiological pressure that one may or may not be able to control or change.

Stress is first perceived in the brain, which goes on high alert, sending nerve impulses to the rest of the body to prepare for fight or flight. Then the adrenal glands release adrenalin (epinephrine) which makes the heart pump faster and the lungs work harder to flood the body with oxygen.

The adrenal glands also produce extra cortisol and other glucocorticoids which help convert the body’s sugars into energy. When the perceived threat passes, levels of adrenalin and cortisol drop.

If this perceived danger comes too often, the cortisol can damage the arteries, weaken the immune system and increase the loss of bone mass, suppress the reproductive system and even affect memory.

Stress is one of the major contributors to Insulin Resistance, the condition that prevents the cell absorbing glucose and insulin properly. It forces glucose to be stored in the bloodstream as fat, which can lead to weight gain and serious disorders like PCOS (Polycystic Ovarian Syndrome), Metabolic Syndrome (Syndrome X), Pre-Diabetes and cardiovascular disease.

By increasing cortisol levels, the liver produces more glucose and puts it into circulation. This may have been happening for many years - perhaps even decades - for people suffering from Insulin Resistance. Increased glucose in the blood, accompanied by an elevated consumption of carbohydrates, causes a compensatory rise in the production of insulin.

This extra insulin causes a lowering of the number of receptor sites on each individual cell, making it much harder for insulin to allow glucose to pass through and be converted to energy. The unused glucose is then stored as fat, which can result in obesity.

The way to break this vicious cycle is to minimize stress, correct your nutrient depletions with pure, natural supplements and increase your exercise regime.

To begin reducing your stress:

  1. Simplify your life. Start by saying “no” to obligations that are not vital to your work or family.
  2. Take 10-20 minutes a day to be alone and focus just on breathing.
  3. Begin to recognize those things over which you have direct control and things you cannot change.

Click here to read more about the Insulite System’s pure natural
nutraceuticals (vitamins, minerals and herbs) that can effect metabolic change.

Measuring Up
Large Waistlines Linked to Metabolic Syndrome

A new study has shown that waist-to-hip ratios are highly efficient in predicting whether you’re at risk of becoming Insulin Resistant or suffering from Metabolic Syndrome (Syndrome X), the cluster disorder that results from Insulin Resistance and substantially increases your chances of developing cardiovascular disease.

To find your waist-to-hip ratio, divide the circumference of your waist in inches by the circumference of your hips in inches. If the resulting difference is greater than 0.8 inch for a woman or 1.0 inch for a man, you risk developing Insulin Resistance or Metabolic Syndrome.

Researchers tracked high waist-to-hip ratios in more than 2,000 people enrolled in the San Antonio Heart Study.* Over a period of 8 years, 32% of subjects who had a high body mass index (BMI) of more than 30kg (see below for conversion) and high waist-to-hip ratios developed Metabolic Syndrome, compared to 10% with low BMI and low waist circumference.

SOURCE: Obesity Research, 2002, 10(9): 923-931

DR. MARY'S VIEW:     “The Body Mass Index is an alternative way of discovering your risk factor.”

Dr. Mary Shackelton
Dr. Shackelton consults in her
Boulder, Colorado Clinic
Many people ask me how to determine if they have either Insulin Resistance or Metabolic Syndrome. Occasionally, they are not able to obtain blood tests to confirm or rule out either condition. Therefore, the BMI is an alternative way and a strong predictor of discovering your risk factor.

A desirable BMI is less than 25. An additional report from the Nurses’ Health Studies found that women with a BMI greater than 29 had triple the risk of coronary heart
disease, compared with women who had a BMI greater than 21.

If your BMI is over 30, you are considered obese and at risk of developing Metabolic Syndrome.

To find your BMI:

  1. Convert your weight into kilograms (divide your weight by 2.2)
  2. Convert your height to inches.
  3. Divide your height by 39.37 to convert the inches to meters.
  4. Multiply this number by the same number e.g. if you are 1.75 meters,
    multiply by 1.75.
  5. Divide your result in #1 by your result in #4. The resulting figure is your BMI.
Dr. Mary Shackelton, MPH ND, is the Medical Director of Insulite Laboratories.

Myth: Calorie restriction is the only thing that reduces weight.

Fact: Reducing calories may be helpful if one has a highly caloric diet. However, weight loss is possible without calorie restriction. It is more beneficial to balance the proportion of foods in the diet i.e. decreasing carbohydrate intake and increasing protein and fat intake.

Regulating blood sugar and insulin levels is more important than focusing on the number of calories consumed. At every meal, try to have 60% of your plate covered by protein, 20% by green vegetables and 20% by fats. You are unlikely to have another weight loss concern if you stick approximately to this ratio.

Dr Mary Shackelton - Medical Director for Insulite Laboratories

Q. Is there anything in the Insulite System that will increase blood pressure?

A. No. In fact, one additional long-term benefit of using the Insulite System is that, by lowering circulating fasting insulin levels, you will actually reduce high blood pressure.

Elevated levels of insulin will actually damage the interior lining of vessels contributing to high blood pressure or hypertension.

A study, published this week by the U.S. Department of Health and Human Services, reveals that 1 in 3 Americans has high blood pressure, an increase that puts millions of more people at risk of heart disease and stroke.

“In just my first few days on the Insulite System, I began to feel that my food was being digested more efficiently. Now, I’m feeling more energetic and am experiencing a greater overall sense of well being.”

Louisville, CO

A new study has found that the humble grapefruit not only promotes weight loss when added to a diet but also seems to influence insulin secretion.

One hundred men and women participated in a study by the Scripps Clinic in San Diego. The group who ate half-a-grapefruit with each meal lost an average of 3.6 pounds over three months while some patients lost 10 pounds. A placebo group lost an average of half-a-pound.

Additionally, researchers discovered that those who ate grapefruit had reduced insulin levels after meals. Glucose levels were also lower, suggesting improved metabolism. Further research is needed is needed to determine exactly what impact grapefruit has on insulin secretion, blood glucose control and Diabetes.
If you’re interested in adding grapefruit to your diet, keep in mind that citrus juice does have the potential to interact with some medications. Check with your pharmacist or doctor. Be Carefull with Medications
Keep Trying
“Victory goes to the most persevering.”
  - Napoleon Bonaparte
Keep up your efforts! Look what it did for The
Duke of Wellington at the Battle of Waterloo.

Take Some Breaks During the Day The human body wasn’t designed to sit at a desk for hours on end. Sedentary habits in the office can lead to weight gain and muscle deterioration. But a busy work schedule sometimes makes it difficult to find the time to follow the U.S Government’s health recommendation of half-an-hour of daily physical activity. However, spending a large chunk of your day in an office doesn’t have to mean you get no exercise. Here are some tips for staying in shape during the work day:
  • Aim to sit at your desk for no longer than 50 minutes at a time before getting up and taking a brief walk or doing some side bends and arm or ankle circles.
  • Take short brisk walks each day if you have a spare ten minutes in your lunch hour.
  • Instead of emailing a message to a colleague down the hall or on another floor, print it out and deliver it by walking to him or her.
  • Suggest a “walk and talk” meeting with workmates.
  • Choose the stairs rather using the elevator.
  • Gentle stretching is a good idea because muscles get tight when hunched, particularly those of the wrist, back, hips, shoulder, chest and hamstrings. To stretch your neck, sit tall in your chair. Relax your neck and gently tilt the head to each side, then front and back, holding each position for a count of 10.
Don’t forget to seek medical advice if you have persistent aches and pains at work.

Drinking water can help you lose weight. For a start, it’s a natural appetite suppressant that contains no calories, fat or cholesterol and is low is sodium.

Water is Good for YouStudies have shown that low consumption of water allows more fat to be deposited in the body instead of being metabolized into energy. So, the more water you drink, the less fat is deposited.

As well as being a great ally when it comes to losing pounds, water is vital for enjoying good health because it regulates the way our bodies function.

If your body isn’t getting enough water, it does everything it can to hold on to the water it does have in order to carry out multiple functions. The end result is bloating, which is cured, believe it or not, by taking in more water.

Once the body is taking in the right amount of water, it rids itself of excess water and begins to run more efficiently, including burning stored fat for energy.

Drinking ice cold water burns calories. The body needs to heat up this water to use it properly and doing so requires energy i.e. calories.

New research suggests there is no scientific basis for the “8-by-8” rule which calls for at least eight 8-ounce glasses of water each day for good health. An expert panel organized by the National Academy of Science concluded that people should let thirst be their guide.

A wedge of lemon or lime adds calorie-free pizzazz to your water while a simple filter, available online or in most grocery or drug stores, can remove impurities from tap water.

Insulite Laboratories is Here for You
You are well on the achieving your desired weight loss goal and the healthy lifestyle you deserve.

Remember that persistence is crucial.
We at Insulite Laboratories are committed to your success and your well being.

We're here to help you. Please contact us with any questions or to order the Insulite System at

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DISCLAIMER: The information contained in this newsletter is for the sole purpose of being informative. This information is not and should not be used or relied upon as medical advice. Always seek the advice of your physician, nurse or other qualified health care provider before you undergo any treatment, take any medication, supplements or other nutritional support, or for answers to any questions you may have regarding a medical condition.

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Photos courtesy of and the U.S. Fish and Wildlife Service.